UNDERSTANDING RECEPTOR AND G PROTEIN INTERACTIONS IN LIVE CELLS

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 受体的膜组织可以被各种膜蛋白改变。Caveolin1是这类蛋白中最重要的成员之一，它广泛地与许多其他蛋白质相互作用，并形成膜结构域。我在表达荧光蛋白的活细胞中进行了FCS、Scanning-FCS、RICS和N&B分析，以了解Caveolin 1如何改变受体的膜组织。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Membrane organization of receptors can be altered by various membrane proteins. Caveolin1 is one of the most important members of this class that widely interacts with many other proteins and is known to form membrane domains. I have performed FCS, scanning-FCS, RICS and N&B analysis in live cells expressing fluorescent proteins to understand how caveolin1 alters membrane organization of receptors.