CORPUS CALLOSUM CHANGES IN MILD ALZHEIMER'S DISEASE

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 轻度阿尔茨海默病和遗忘型轻度认知障碍患者的胼胝体改变 将评估健康对照组和阿尔茨海默病和轻度认知障碍患者的胼胝体形态。将根据已定义的跟踪协议手动划定胼胝体区域。然后，将使用基于计算表面的技术来以高分辨率对膝盖骨厚度进行编码，以进行分组比较。我们希望利用神经成像实验室(LONI)开发的一种基于表面的计算方法来分析膝盖骨厚度。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Corpus Callosum Changes in Mild Alzheimer Disease and Amnesic Mild Cognitive Impairment Corpus callosum morphology will be assessed in healthy controls and patients with Alzheimer's disease and Mild Cognitive impairment. The corpus callosum region will be delineated manually following a defined tracing protocol. Computational surfaced-based techniques to encode callosal thickness at high resolution will then be applied to compare groups. We wish to analyze callosal thickness utilizing a computational surface-based approach that was developed at the Laboratory of Neuro Imaging (LONI).