International

国际的

基本信息

批准号：
7684977
负责人：
Harvey Michael Friedman
金额：
$ 25.51万
依托单位：
UNIVERSITY OF PENNSYLVANIA
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-09-25 至 2014-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7684977
关键词：
AIDS prevention AIDS/HIV problem Acquired Immunodeficiency Syndrome Address Adherence Adopted Area Award Behavioral Botswana Clinical Collaborations Consent Country Development Education Enrollment Environment Feasibility Studies Fellowship Foundations Funding Future Goals Government Grant HIV Health Health Personnel Home environment Hospitals Housing Human Resources Human Subject Research Infection Informed Consent International Internet Investigation Knowledge Laboratories Leadership Location Malignant neoplasm of cervix uteri Medical Students Mentors Mission Molecular Immunology Monoclonal Antibody R24 Nursing Research Opportunistic Infections Prevention education Process Research Research Ethics Committees Research Infrastructure Research Personnel Research Project Grants Sampling Scientist Services Shipping Ships Site Study Subject Supervision Testing Time Training United States National Institutes of Health Universities Virus Woman Work base clinical care experience innovation interest international center medical schools meter patient oriented research patient population programs research study skills

项目摘要

The Specific Aims of Core I are: 1) To educate, train and mentor investigators from Botswana and Penn interested in global health research; and 2) To advance knowledge about HIV/AIDS and its complications in Botswana by performing high quality epidemiologic and patient-oriented research. Penn has developed strong clinical and educational programs in Botswana based primarily on PEPFAR funding, which provides the clinical base for our research. The Core provides the following services: i) Advising Penn investigators on the feasibility of studies proposed for Botswana; ii) Providing on-site supervision of research nurses and technicians; iii) Assisting with informed consent at the Ministry of Health, Botswana hospitals and Penn; iv) Collecting and processing samples for testing, storage or shipping; v) Providing office space and Internet for Core personnel; vi) Providing housing for Penn investigators while working in Botswana; and vii) Identifying collaborators at the University of Botswana and the Ministry of Health to work with Penn scientists, which is consistent with our goal of building research capacity in country. During the past 4 years, we helped the University of Botswana get its first-ever NIH grant; Penn CFAR investigators obtained 6 CFAR Developmental Grants for studies in Botswana; Penn scientists obtained 2 Doris Duke Foundation Awards, including a 5-year medical student research fellowship grant; and we obtained Gates-Merck Foundation funding for HIV-TB education, prevention and treatment of health care workers in Botswana. Currently, the Core is supporting 19 studies in Botswana. In the next funding cycle we will expand our research office and laboratory infrastrucute through construction of a building in collaboration with the Ministry of Health and the University of Botswana School of Medicine; we will expand our research agenda in the areas of opportunistic infections, HIV-TB co-infections, adherence to therapy, HIV prevention, and cervical cancer in HIV infected women. Core I has enhanced the capabilities of Penn and Botswana investigators to do high quality global health research that is addressing issues that are relevant to the citizens of Botswana.

核心I的具体目的是：1）教育，培训和导师的调查员来自博茨瓦纳和宾夕法尼亚对全球健康研究感兴趣； 2）促进有关艾滋病毒/艾滋病的知识及其并发症博茨瓦纳通过进行高质量的流行病学和面向患者的研究。宾夕法尼亚州已经发展博茨瓦纳的强大临床和教育计划主要基于PEPFAR资金，该计划提供我们研究的临床基础。核心提供以下服务：i）为宾夕法尼亚州调查人员提供建议关于博茨瓦纳提出的研究的可行性； ii）提供研究护士的现场监督技术人员； iii）协助卫生部，博茨瓦纳医院和宾夕法尼亚州的知情同意； iv）收集和处理样品进行测试，存储或运输； v）提供办公空间和互联网核心人员； vi）在博茨瓦纳（Botswana）工作时为宾夕法尼亚州调查人员提供住房；和vii）识别博茨瓦纳大学和卫生部与宾夕法尼亚州科学家合作的合作者与我们在国家建立研究能力的目标一致。在过去的四年中，我们帮助了博茨瓦纳大学获得了有史以来的首个NIH赠款； Penn CFAR调查人员获得了6个CFAR 博茨瓦纳研究的发展赠款；宾夕法尼亚州科学家获得了2个多丽丝·杜克基金会奖项，包括5年的医学学生研究奖学金；我们获得了盖茨 - 梅克基金会博茨瓦纳的卫生保健工作者的HIV-TB教育，预防和治疗的资金。目前，核心正在支持博茨瓦纳的19项研究。在下一个融资周期中，我们将通过施工扩大研究办公室和实验室基础与卫生部和博茨瓦纳大学医学院合作的建筑物；我们将在机会主义感染，HIV-TB共同感染，遵守方面扩展研究议程在艾滋病毒感染的妇女中进行治疗，预防HIV和宫颈癌。核心I增强了宾夕法尼亚州和博茨瓦纳调查人员的能力，以进行高质量的全球健康正在解决与博茨瓦纳公民有关的问题的研究。