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International

国际的

基本信息

批准号：
7684977
负责人：
Harvey Michael Friedman
金额：
$ 25.51万
依托单位：
UNIVERSITY OF PENNSYLVANIA
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-09-25 至 2014-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7684977
关键词：
AIDS prevention AIDS/HIV problem Acquired Immunodeficiency Syndrome Address Adherence Adopted Area Award Behavioral Botswana Clinical Collaborations Consent Country Development Education Enrollment Environment Feasibility Studies Fellowship Foundations Funding Future Goals Government Grant HIV Health Health Personnel Home environment Hospitals Housing Human Resources Human Subject Research Infection Informed Consent International Internet Investigation Knowledge Laboratories Leadership Location Malignant neoplasm of cervix uteri Medical Students Mentors Mission Molecular Immunology Monoclonal Antibody R24 Nursing Research Opportunistic Infections Prevention education Process Research Research Ethics Committees Research Infrastructure Research Personnel Research Project Grants Sampling Scientist Services Shipping Ships Site Study Subject Supervision Testing Time Training United States National Institutes of Health Universities Virus Woman Work base clinical care experience innovation interest international center medical schools meter patient oriented research patient population programs research study skills

项目摘要

The Specific Aims of Core I are: 1) To educate, train and mentor investigators from Botswana and Penn interested in global health research; and 2) To advance knowledge about HIV/AIDS and its complications in Botswana by performing high quality epidemiologic and patient-oriented research. Penn has developed strong clinical and educational programs in Botswana based primarily on PEPFAR funding, which provides the clinical base for our research. The Core provides the following services: i) Advising Penn investigators on the feasibility of studies proposed for Botswana; ii) Providing on-site supervision of research nurses and technicians; iii) Assisting with informed consent at the Ministry of Health, Botswana hospitals and Penn; iv) Collecting and processing samples for testing, storage or shipping; v) Providing office space and Internet for Core personnel; vi) Providing housing for Penn investigators while working in Botswana; and vii) Identifying collaborators at the University of Botswana and the Ministry of Health to work with Penn scientists, which is consistent with our goal of building research capacity in country. During the past 4 years, we helped the University of Botswana get its first-ever NIH grant; Penn CFAR investigators obtained 6 CFAR Developmental Grants for studies in Botswana; Penn scientists obtained 2 Doris Duke Foundation Awards, including a 5-year medical student research fellowship grant; and we obtained Gates-Merck Foundation funding for HIV-TB education, prevention and treatment of health care workers in Botswana. Currently, the Core is supporting 19 studies in Botswana. In the next funding cycle we will expand our research office and laboratory infrastrucute through construction of a building in collaboration with the Ministry of Health and the University of Botswana School of Medicine; we will expand our research agenda in the areas of opportunistic infections, HIV-TB co-infections, adherence to therapy, HIV prevention, and cervical cancer in HIV infected women. Core I has enhanced the capabilities of Penn and Botswana investigators to do high quality global health research that is addressing issues that are relevant to the citizens of Botswana.

CORE I的具体目标是：1)教育、培训和指导来自博茨瓦纳和宾夕法尼亚的调查人员对全球卫生研究感兴趣；以及2)增进对艾滋病毒/艾滋病及其并发症的认识博茨瓦纳通过开展高质量的流行病学和以病人为中心的研究。宾夕法尼亚大学已经开发出博茨瓦纳强大的临床和教育项目主要基于PEPFAR的资助，该项目提供这是我们研究的临床基础。中心提供以下服务：i)为宾夕法尼亚大学的调查人员提供咨询关于拟议为博茨瓦纳进行的研究的可行性；二)为研究护士提供现场监督和技术人员；三)协助卫生部、博茨瓦纳医院和宾夕法尼亚大学的知情同意；四) 收集和处理样品，用于测试、储存或运输；v)提供办公场所和互联网核心人员；vi)在博茨瓦纳工作期间为宾夕法尼亚大学调查人员提供住房；和vii)确定博茨瓦纳大学和卫生部的合作者与宾夕法尼亚大学的科学家合作，这是与我们在国家建设研究能力的目标一致。在过去的4年里，我们帮助博茨瓦纳大学首次获得NIH拨款；宾夕法尼亚大学CFAR调查人员获得6 CFAR 为博茨瓦纳的研究提供发展补助金；宾夕法尼亚大学的科学家获得了两项多丽丝·杜克基金会奖，包括一项为期5年的医科学生研究奖学金；我们还获得了盖茨-默克基金会为博茨瓦纳医护人员的艾滋病毒-结核病教育、预防和治疗提供资金。目前， CORE正在支持博茨瓦纳的19项研究。在下一个资金周期中，我们将通过建设扩大我们的研究办公室和实验室基础设施与卫生部和博茨瓦纳大学医学院合作建造一栋大楼；我们将在机会性感染、艾滋病毒-结核病合并感染、依从性等领域扩大研究议程用于治疗、艾滋病毒预防和艾滋病毒感染妇女的宫颈癌。 CORE I增强了宾夕法尼亚大学和博茨瓦纳研究人员的能力，以实现高质量的全球卫生正在解决与博茨瓦纳公民相关的问题的研究。