Combined Adult and Pediatric Infectious Disease Postdoctoral Training Grant

项目摘要 该机构培训补助金（T32）是佩雷尔曼学校的一项提案的重新提交， 医学（PSOM）在宾夕法尼亚大学（Penn）和费城儿童医院（CHOP） 培养医学博士和医学博士/博士研究员从事微生物学，微生物免疫学的实验室研究 以及微生物组在健康和疾病中的作用。这个应用程序结合了人才和资源 可在两个独立的，但联系机构，宾夕法尼亚大学和CHOP。我们每年申请3个名额， 每年招收一名研究员，提供长达3年的支持。17位非常有成就的教职员工， 美国国立卫生研究院的赠款被列为导师。哈维弗里德曼，医学博士，从成人传染病科将 担任项目主任（PD），CHOP儿科主席Joseph St. Geme医学博士将担任 助理警察9名教师导师来自医学系，4名来自医学系， 微生物学，儿科2名，皮肤科1名， 威斯塔研究所。辅导员包括6名妇女、1名来自代表性不足的少数群体的成员、10名来自 医学博士或医学博士/博士学位和7个博士学位; 3个助理，4个副教授和10个教授。 申请人池将主要来自成人和儿童传染病博士后培训 计划，但招生将开放给所有部门和部门在宾夕法尼亚州和CHOP谁拥有MD和 MD/PhD博士后研究员，有兴趣从事微生物学，免疫学和 人体微生物组有兴趣在这些学科从事板凳研究的候选人很好 在各司和部门的研究金受训人员中， 突出了我们申请人的优势。有兴趣申请T32赠款职位的研究员将 一般在他们的奖学金的第一年申请，期望他们将进入赠款在他们的 第二年奖学金。研究员将通过提交他们的简历，以前的实验室导师的推荐信来申请 和他们的奖学金主任，以及他们在本科和研究生培训期间的成绩记录。 每一个被选中的实习生都将有一个科学导师（实验室PI）和一个职业导师（高级导师）。 Penn或CHOP的教员）。执行委员会将审查学员的研究进展 每半年一次，一个咨询委员会由两名来自宾夕法尼亚大学以外的科学家和一名来自宾夕法尼亚大学的科学家组成。 将每年与学员见面，审查他们的进展情况。 宾夕法尼亚大学和CHOP的生物医学研究培训环境和资源是特殊的。的 导师的卓越品质、申请人的卓越资历和行政人员的奉献精神 委员会确保每一位学员都能得到最高质量的指导，这增加了我们的信心。 我们将解决迫切需要培养未来的医生科学家领导人的学科， 微生物学、微生物免疫学和微生物组学研究。

PROJECT SUMMARY This Institutional Training Grant (T32) is a resubmission of a proposal from the Perelman School of Medicine (PSOM) at the University of Pennsylvania (Penn) and the Children's Hospital of Philadelphia (CHOP) to train MD and MD/PhD fellows pursuing careers doing bench research in microbiology, microbial immunology and the role of the microbiome in health and disease. This application combines the talent and resources available at two independent, but linked institutions, Penn and CHOP. We are requesting 3 slots annually to enroll one fellow each year for up to 3 years of support. Seventeen highly accomplished faculty members with active NIH grants are listed as mentors. Harvey Friedman, MD, from the Adult Infectious Disease Division will serve as Program Director (PD) and Joseph St. Geme, MD, Chairman of Pediatrics at CHOP will be the associate-PD. Nine faculty mentors are from the Departments of Medicine, 4 from the Department of Microbiology, 2 from the Department of Pediatrics, 1 from the Department of Dermatology, and 1 from the Wistar Institute. The mentors include 6 women; a member from an underrepresented minority group; 10 with MD or MD/PhD degrees and 7 with PhD degrees; 3 Assistant, 4 Associate and 10 Professors. The applicant pool will come primarily from the Adult and Pediatric Infectious Diseases postdoctoral training programs, but enrollment will be open to all divisions and departments at Penn and CHOP who have MD and MD/PhD postdoctoral fellows interested in pursuing bench research careers in microbiology, immunology and the human microbiome. Candidates interested in pursuing bench research careers in these disciplines are well represented among the fellowship trainees in the divisions and departments with mentors on this grant, which highlights the strengths of our applicant pool. Fellows interested in applying for a position on the T32 grant will generally apply during their first year of fellowship with the expectation that they will enter the grant in their second fellowship year. Fellows will apply by submitting their CVs, letters of reference from prior lab mentors and their fellowship director, and a record of their grades during undergraduate and postgraduate training. Each trainee selected for a position will have a scientific mentor (the lab PI) and a career mentor (a senior faculty member at Penn or CHOP). The Executive Committee will review the research progress of trainees semi-annually and an Advisory Committee comprised of two scientists from outside Penn and one from Penn will meet with trainees to review their progress annually. The environment and resources at Penn and CHOP for training in biomedical research are exceptional. The superb quality of the mentors, the outstanding credentials of the applicants and the dedication of the Executive Committee to ensure that every trainee receives the highest quality mentoring possible adds to our confidence that we will be addressing the urgent need to train the future physician scientist leaders in the disciplines of microbiology, microbial immunology, and microbiome research.