AR CAREER DEVELOPMENT COBRE: EXPERIMENTAL CORE

AR 职业发展 COBRE：实验核心

• 批准号: 7960484
• 负责人: ROBERT D SKINNER
• 金额: $ 26.48万
• 依托单位: UNIV OF ARKANSAS FOR MED SCIS
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7960484
• 关键词: Arousal; Award; Blood flow; Calcium; Centers of Research Excellence; Computer Retrieval of Information on Scientific Projects Database; Computer software; Core Facility; Dyes; Electrophysiology (science); Exhibits; Funding; Grant; Human; Image Analysis; In Vitro; Institution; Measures; Microscope; Near-Infrared Spectroscopy; Performance; Reaction Time; Relative (related person); Research; Research Personnel; Resources; Source; Speed; Testing; United States National Institutes of Health; career development; cognitive function; fluorescence imaging; frontal lobe; response; translational neuroscience; vigilance; voltage

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Experimental Core now has three Core Facilities. The Electrophysiology Core Facility undertakes studies related to human midlatency uditory evoked responses as arousal (pre-attentional) measures, attentional measures as exhibited by performance of a Psychomotor Vigilance Task (PVT) reaction time test, cognitive functions as exhibited in the performance of an Operant Test Battery (OTB), and relative frontal lobe blood flow as measured using Near Infrared Spectroscopy (NIRS). The Image Analysis Core was developed during Year 1 of the award and consists of a confocal microscope with fluorescence and image analysis software, along with a high speed camera for visualizing voltage-dependent and calcium dyes in the in vitro recording rig.

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 实验核心现在有三个核心设施。 电生理学核心设施进行与人类中潜伏期诱发反应相关的研究，作为唤醒（前注意力）测量，通过执行心理警戒任务（PVT）反应时间测试显示的注意力测量，在操作测试组合（OTB）中显示的认知功能，以及使用近红外光谱（NIRS）测量的相对额叶血流。 图像分析核心是在该奖项的第一年开发的，包括一个带有荧光和图像分析软件的共聚焦显微镜，沿着一个高速相机，用于在体外记录装置中可视化电压依赖性和钙染料。