SYNTHESIS OF NOVEL PRECURSORS TO PROPOSED ANTIBACTERIAL AGENTS

所提出的抗菌剂的新型前体的合成

• 批准号: 7960314
• 负责人: Jetty L Duffy-Matzner
• 金额: $ 3.47万
• 依托单位: UNIVERSITY OF SOUTH DAKOTA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-16 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7960314
• 关键词: Anti-Bacterial Agents; Biomedical Research; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Heterocyclic Compounds; Institution; Mass Fragmentography; Methods; Polyesters; Research; Research Infrastructure; Research Personnel; Resources; Source; South Dakota; Spectrometry; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Synthesis Chemistry; United States National Institutes of Health; Work; novel; tool

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This work will utilize synthetic chemistry tools to produce novel heterocyclic compounds that will be examined as possible precursors for a proposed polyester antibacterial macrocycle. The compounds will be prepared with an inert manifold and examined via standard spectrometry and spectroscopy methods to include: FTIR, FTNMR, and GCMS.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 这项工作将利用合成化学工具来生产新型杂环化合物，这些化合物将作为拟议的聚酯抗菌大环化合物的可能前体进行研究。 这些化合物将用惰性歧管制备，并通过标准光谱测定和光谱方法进行检查，包括：FTIR、FTNMR 和 GCMS。