IMMUNE MONITORING LAB

免疫监测实验室

• 批准号: 7944763
• 负责人: LELAND H HARTWELL
• 金额: $ 23.75万
• 依托单位: FRED HUTCHINSON CANCER RESEARCH CENTER
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-03-10 至 2013-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7944763
• 关键词: Adoptive Transfer; Affinity; Alleles; Analysis of Variance; Antibodies; Antigens; B-Lymphocytes; Binding; Biological; Biological Assay; Biological Testing; Cancer Center Support Grant; Cancer Patient; Cell Separation; Cell physiology; Cell surface; Cells; Cellular Assay; Chromium; Circular DNA; Clonal Expansion; Complex; Consultations; Cytolysis; Cytotoxic T-Lymphocytes; DNA; DNA Sequence Rearrangement; Data Analyses; Dendritic Cells; Development; Enzyme-Linked Immunosorbent Assay; Evaluation; Excision; Experimental Designs; Flow Cytometry; Fluorescent Dyes; Fluorochrome; Frequencies; Gel Chromatography; Genetic Polymorphism; Genome; Gerda brand of difluprednate; HLA-A gene; HLA-B Antigens; HLA-C Antigens; Housing; Human; Human Resources; Immune; Immune response; Immunologic Monitoring; Immunologics; Immunology; Immunotherapy; In Vitro; Individual; Knowledge; Label; Laboratories; Length; Lymphocyte; MHC Class I Genes; Macaca; Malignant Neoplasms; Measurement; Measures; Mediator of activation protein; Methodology; Methods; Microspheres; Mitogens; Mixed Lymphocyte Culture Test; Molecular; Molecular Analysis; Mus; Names; Natural Killer Cells; Nature; Output; Peptide/MHC Complex; Peptides; Performance; Peripheral; Peripheral Blood Mononuclear Cell; Phenotype; Population; Procedures; Production; Proliferating; Proteins; Radioimmunoassay; Reaction; Reader; Reagent; Relative (related person); Request for Applications; Research; Research Personnel; Resource Sharing; Resources; Reverse Transcriptase Polymerase Chain Reaction; Role; Sampling; Services; Spottings; Staining method; Stains; Stem cell transplant; Streptavidin; Structure; T-Cell Receptor; T-Cell Receptor-Rearrangement Excision DNA Circles; T-Lymphocyte; TRB@ gene cluster; Techniques; Technology; Thymidine; Thymus Gland; Time; Training; Universities; Washington; antibody conjugate; base; beta Chain Antigen T Cell Receptor; beta-2 Microglobulin; cell mediated lymphocytolysis test; complementarity-determining region 3; cytokine; design; enzyme linked immunospot assay; killings; monocyte; monomer; reconstitution; response; tool

The Immune Monitoring Lab provides investigators with a broad spectrum of services and expertise to carry out a range of assays of human proteins and other biological mediators and perform studies where precise evaluations of the immunologic response are required. Resource services include the production of peptide- MHC Class-l tetramers, unique reagents for accessing antigen-specific T cells; molecular assays for T cell receptor (TCR) related analysis, cellular assays for determining cellular function and analytical services using ELISA and Luminex microbead methodology. This application requests continued support for a resource which fulfills an essential role for research within the Fred Hutchinson/University of Washington Cancer Consortium.

免疫监测实验室为研究人员提供广泛的服务和专业知识