Photomultiplier Chip(TM) for ultra-fast TOF-PET
Photomultiplier Chip(TM) for ultra-fast TOF-PET
批准号:
7671851
负责人:
ERIC S HARMON
金额:
$19.79万
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-06-01 至 2010-11-30
关键词:
AgingAlgorithmsAnimalsAreaAttentionBromidesBuild-itCeriumCharacteristicsChargeCherry - dietaryClinicalComplementCoupledDataDetectionDevicesDiscipline of Nuclear MedicineDiscriminationDiseaseDoseElectronicsElectronsEventExhibitsFailureGamma RaysGoalsHeightHourHumanImageIsotopesLanthanumMeasuresMethodsModelingMusNoiseNuclearOrganPatientsPerformancePhasePhotonsPhysiologic pulsePositronPositron-Emission TomographyProbabilityPropertyQiRadiationRadiation DosageRadioisotopesReadingRecordsRelianceReportingResearchResolutionRiskSNR1ScienceSemiconductorsSignal TransductionSiliconSpeedStagingSystemTechnologyTimeTubeUncertaintyWidthabsorptionbaseclinically relevantdesigndetectordosagegallium arsenideimprovedinnovationinterestionizationlecturesmennanosecondnovelphotomultiplierpreferencepublic health relevancequantumreconstructionresearch and developmentsolid statestemsuccesssymposiumtime usewhole body imaging
中文摘要
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英文摘要
DESCRIPTION (provided by applicant): LightSpin Technologies, Inc., proposes to develop a photodetector module capable of providing ultra-fast timing resolution for TOF-PET applications. The photodetector module exploits LightSpin's ultra-fast Photomultiplier ChipTM technology, which is capable of achieving single-photon timing jitter below 20 ps across large photo-sensitive areas (more than 10 mm2), while maintaining excellent quantum efficiency (above 50%), linearity and dynamic range. The breakthrough stems from LightSpin's innovation in semiconductor single-photon detectors and monolithically integrated electronic circuits. The photodetector module will be coupled to a fast scintillator (cerium-doped lanthanum bromide), providing an ultimate capability to achieve ultra-fast TOF-PET with coincidence resolution better than 50 ps FWHM. In Phase I, LightSpin will demonstrate good timing performance in the photodetector itself and in a simple photodetector module coupled to a scintillator. In Phase II, LightSpin will develop a full PET detector camera module, including multiple photodetectors and a readout ASIC to report X, Y, timing, and energy of incident gamma rays. PUBLIC HEALTH RELEVANCE:The proposed detector module allows a radiation dose 50 times smaller than in conventional PET scanners to give a better image. The innovation is an ultra-fast detector module enabling 40 ps time-of-flight PET, with 7 times better signal-to-noise ratio.
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GaAs Photomultiplier Chip(TM) for TOF-PET
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批准号:8720733
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项目类别:
-
资助金额:$51.2万
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财政年份:2010
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负责人:ERIC S HARMON
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依托单位:
GaAs Photomultiplier Chip(TM) for TOF-PET
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批准号:8524756
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项目类别:
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资助金额:$51.93万
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财政年份:2010
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负责人:ERIC S HARMON
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依托单位:
Ultimate Sensitivity Solid State Photodetector
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批准号:6833656
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项目类别:
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资助金额:$26.31万
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财政年份:2004
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负责人:ERIC S HARMON
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依托单位:
PET Detector
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批准号:7479831
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项目类别:
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资助金额:$24.06万
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财政年份:2004
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负责人:ERIC S HARMON
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依托单位:
PET Detector
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批准号:7228412
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项目类别:
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资助金额:$50.94万
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财政年份:2003
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负责人:ERIC S HARMON
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依托单位:
海外基金