Photomultiplier Chip(TM) for ultra-fast TOF-PET

描述（由申请人提供）：LightSpin Technologies，Inc.，提出开发一种能够为TOF-PET应用提供超快定时分辨率的光电探测器模块。该光电探测器模块采用LightSpin的超快光电倍增管芯片TM技术，能够在大面积光敏区域（超过10 mm 2）实现低于20 ps的单光子时序抖动，同时保持出色的量子效率（50%以上）、线性度和动态范围。这一突破源于LightSpin在半导体单光子探测器和单片集成电子电路方面的创新。光电探测器模块将耦合到一个快速闪烁体（铈掺杂溴化镧），提供了一个最终的能力，以实现超快TOF-PET符合分辨率优于50 ps的半高宽。在第一阶段，LightSpin将在光电探测器本身和耦合到闪烁体的简单光电探测器模块中展示良好的定时性能。在第二阶段，LightSpin将开发一个完整的PET探测器相机模块，包括多个光电探测器和一个读出ASIC，以报告入射伽马射线的X，Y，定时和能量。公共卫生相关性：拟议的探测器模块允许辐射剂量比传统PET扫描仪小50倍，以提供更好的图像。该创新是一种超快探测器模块，可实现40 ps的飞行时间PET，信噪比提高7倍。

DESCRIPTION (provided by applicant): LightSpin Technologies, Inc., proposes to develop a photodetector module capable of providing ultra-fast timing resolution for TOF-PET applications. The photodetector module exploits LightSpin's ultra-fast Photomultiplier ChipTM technology, which is capable of achieving single-photon timing jitter below 20 ps across large photo-sensitive areas (more than 10 mm2), while maintaining excellent quantum efficiency (above 50%), linearity and dynamic range. The breakthrough stems from LightSpin's innovation in semiconductor single-photon detectors and monolithically integrated electronic circuits. The photodetector module will be coupled to a fast scintillator (cerium-doped lanthanum bromide), providing an ultimate capability to achieve ultra-fast TOF-PET with coincidence resolution better than 50 ps FWHM. In Phase I, LightSpin will demonstrate good timing performance in the photodetector itself and in a simple photodetector module coupled to a scintillator. In Phase II, LightSpin will develop a full PET detector camera module, including multiple photodetectors and a readout ASIC to report X, Y, timing, and energy of incident gamma rays. PUBLIC HEALTH RELEVANCE:The proposed detector module allows a radiation dose 50 times smaller than in conventional PET scanners to give a better image. The innovation is an ultra-fast detector module enabling 40 ps time-of-flight PET, with 7 times better signal-to-noise ratio.