Developing a Sustainable Consumer Clearinghouse for Translational Depression and

描述（由申请人提供）：转化研究是医疗保健进步的基石。然而，促进研究参与者或消费者与研究人员之间的沟通几十年来一直是一个挑战。由于缺乏研究参与者、误解、污名化，甚至消费者对研究误用和滥用的恐惧，消费者和研究者观点的分歧导致研究失败。这些挑战对于不同的疾病是独特的，并且在抑郁症和双相情感障碍的研究中可能会加剧，部分原因是抑郁症、双相情感障碍和其他情绪障碍所施加的固有行为限制，在特定疾病状态下接触消费者的困难，共同发生的疾病的流行，以及目前可用于支持这些联系的社区或公共资源很少。拟议的项目旨在通过创建消费者抑郁症-双相情感障碍研究信息中心，为抑郁症、双相情感障碍和情绪研究开发一个开创性的、可持续的项目。信息交换中心将为研究人员提供机会，与有兴趣参与转化抑郁症研究的消费者直接联系，并为消费者提供机会，对这项研究的优先事项、方向和评估发表意见。信息交换中心将建立在一个已经存在的伙伴关系之上，这个伙伴关系包括全国领先的消费者权益组织之一（抑郁症和双相情感障碍支持联盟），全国首个综合抑郁症中心（密歇根大学综合抑郁症中心），以及未来的全国抑郁症中心网络。它将采用社交网络策略、社区参与和个性化外展来实现其目标。该计划将在密歇根州和俄亥俄州北部地区启动，评估其有效性，然后通过扩大到国家合作伙伴使其可持续发展。

DESCRIPTION (provided by applicant): Translational research is the cornerstone of health care advances. However, facilitating communication between research participants or consumers and investigators has been a challenge for decades. Divergent consumer and investigator perspectives have led to failed research studies due to lack of research participants, misunderstandings, stigma, and even fear of research misuse and abuse among consumers. These challenges are unique for different disorders, and may be exacerbated in depression and bipolar research, due in part to the inherent behavioral constraints imposed by depression, bipolar, and other mood disorders, difficulty in reaching consumers in specific disease states, the prevalence of co-occurring disorders, and the few community or public resources currently available to support these connections. The proposed program aims to develop a groundbreaking, sustainable program for depression, bipolar and mood research by creating a Consumer Depression-Bipolar Research Clearinghouse. The Clearinghouse would provide researchers the opportunity to link directly with consumers interested in participating in translational depression research, and would provide consumers the opportunity to have a voice in the priorities, direction and evaluation of this research. The Clearinghouse will build upon a pre-existing partnership among one of the nation's leading consumer advocacy groups (Depression and Bipolar Support Alliance), the nation's inaugural Comprehensive Depression Center (University of Michigan Comprehensive Depression Center), and in the future, the National Network of Depression Centers. It will employ social networking strategies, community engagement and personalized outreach to achieve its aims. The program will be launched regionally in Michigan and northern Ohio, evaluated for effectiveness, and then made sustainable through expansion to national partners. PUBLIC HEALTH RELEVANCE: The proposed program aims to develop a sustainable program to promote depression, bipolar and mood research. The Consumer Depression-Bipolar Research Clearinghouse would provide researchers the opportunity to identify consumers interested in participating in translational depression research, and would provide consumers the opportunity to have a voice in the priorities, direction and evaluation of depression research.