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Echocardiograph and Vascular Doppler

超声心动图和血管多普勒

基本信息

批准号：
7794037
负责人：
DAVID HERLIE ROBERTSON
金额：
$ 20.14万
依托单位：
VANDERBILT UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-04-08 至 2011-04-07
项目状态：
已结题

项目摘要

DESCRIPTION (provided by applicant): Clinical research in humans is dependent on an accurate assessment of the subjects' cardiovascular anatomy and physiology. The health of the public is dependent on medical science finding cures for heart disease, the number one killer of men and women in the US, cures and prevention of cancer, prevention and management of diabetes and prevention of obesity. Research interventions that affect health such as diet, exercise, medications and devices are evaluated by equipment that measures heart and blood vessel function. Echocardiography and vascular Doppler are assessment tools used in clinical research to evaluate the baseline characteristics of subjects' physiology and their response to clinical research interventions. Echocardiography is a measurement of heart structure and function. Vascular Doppler is a measurement of blood vessel structure and function. A research and clinical method of assessing the function and structure of the heart and blood vessels is through echocardiography and vascular Doppler using sound waves. We are requesting a Philips iE33 Echocardiograph with a Vascular Doppler probe and analysis software to support the clinical research program in the NCRR/CTSA--funded Clinical Research Center. The cost of the equipment is $206,760. This shared equipment will be administered through the Clinical Research Center and available for use by the ~560 active research protocols and future research protocols conducted on the Center. PUBLIC HEALTH RELEVANCE: An accurate assessment of human anatomy and physiology is critical to the success of clinical research. Echocardiography and vascular Doppler are assessment tools used in clinical research to evaluate the baseline characteristics of subjects' physiology and their response to clinical research interventions. This proposal requests financial support to purchase a Philips iE33 echocardiograph with a vascular Doppler probe and analysis software to be shared among clinical investigators who are seeking therapies for the diseases that are affecting the health of the nation.

描述（由申请人提供）：人类临床研究取决于对受试者心血管解剖学和生理学的准确评估。公众的健康取决于医学科学对心脏病（美国男性和女性的头号杀手）的治疗方法、癌症的治疗和预防、糖尿病的预防和管理以及肥胖的预防。影响健康的研究干预措施，如饮食、运动、药物和设备，通过测量心脏和血管功能的设备进行评估。超声心动图和血管多普勒是临床研究中使用的评估工具，用于评估受试者生理学的基线特征及其对临床研究干预的反应。超声心动图是心脏结构和功能的测量。血管多普勒是血管结构和功能的测量。评估心脏和血管的功能和结构的研究和临床方法是通过超声心动图和使用声波的血管多普勒。我们需要一台配备血管多普勒探头和分析软件的飞利浦 iE33 超声心动图仪，以支持 NCRR/CTSA 资助的临床研究中心的临床研究项目。设备成本为 206,760 美元。该共享设备将通过临床研究中心进行管理，可供约 560 个正在进行的研究方案和在该中心进行的未来研究方案使用。公共卫生相关性：准确评估人体解剖学和生理学对于临床研究的成功至关重要。超声心动图和血管多普勒是临床研究中使用的评估工具，用于评估受试者生理学的基线特征及其对临床研究干预的反应。该提案要求提供财政支持，购买一台带有血管多普勒探头和分析软件的飞利浦 iE33 超声心动图仪，以便在正在寻求治疗影响国家健康的疾病的临床研究人员之间共享。