Toll-like Receptors: Novel targets of neuroprotection in ischemic brain injury

Toll 样受体：缺血性脑损伤神经保护的新靶点

• 批准号: 8043999
• 负责人: MARY P STENZEL-POORE
• 金额: $ 33.01万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-15 至 2014-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8043999
• 关键词: Acute; Address; Adverse effects; Agonist; Animals; Atherosclerosis; Attenuated; Bacterial DNA; Biology; Blood - brain barrier anatomy; Bone Marrow; Brain; Brain Injuries; Bromodeoxyuridine; Cardiac; Cardiovascular Diseases; Cardiovascular system; Carotid Endarterectomy; Cause of Death; Cell Death; Cell Survival; Cells; Cerebrovascular Disorders; Cessation of life; Chemicals; Coronary Arteriosclerosis; Coronary Artery Bypass; DNA Markers; Development; Diagnostic; Dissection; Dose; Endotoxins; Event; Family; Future; Genomics; Goals; Health; Hematopoietic; Hour; Human; Imiquimod; Immune Cell Activation; Infiltration; Inflammation; Inflammatory; Injury; Interferon-beta; Ischemia; Ischemic Brain Injury; Knock-out; Knowledge; Label; Laboratories; Lesion; Life Expectancy; Ligands; Lipopolysaccharides; Location; Molecular; Morbidity - disease rate; Mus; Nature; Neurologic; Oligonucleotides; Operative Surgical Procedures; Outcome; Pathogenesis; Pathway interactions; Patients; Procedures; Process; Quality of life; Radiation; Receptor Signaling; Relative (related person); Risk; Role; Signal Pathway; Signal Transduction; Stimulus; Stroke; TLR4 gene; TLR7 gene; TNF gene; Testing; Therapeutic; Toll-like receptors; Translations; United States; Work; cytokine; disability; heart valve replacement; high risk; improved; member; mortality; neuroprotection; novel; pathogen; patient population; preconditioning; prophylactic; receptor; repaired; response; response to injury; stroke therapy; subcutaneous