Toll-like Receptors: Novel targets of neuroprotection in ischemic brain injury
Toll-like Receptors: Novel targets of neuroprotection in ischemic brain injury
批准号:
8043999
负责人:
MARY P STENZEL-POORE
金额:
$33.01万
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-04-15 至 2014-03-31
关键词:
AcuteAddressAdverse effectsAgonistAnimalsAtherosclerosisAttenuatedBacterial DNABiologyBlood - brain barrier anatomyBone MarrowBrainBrain InjuriesBromodeoxyuridineCardiacCardiovascular DiseasesCardiovascular systemCarotid EndarterectomyCause of DeathCell DeathCell SurvivalCellsCerebrovascular DisordersCessation of lifeChemicalsCoronary ArteriosclerosisCoronary Artery BypassDNA MarkersDevelopmentDiagnosticDissectionDoseEndotoxinsEventFamilyFutureGenomicsGoalsHealthHematopoieticHourHumanImiquimodImmune Cell ActivationInfiltrationInflammationInflammatoryInjuryInterferon-betaIschemiaIschemic Brain InjuryKnock-outKnowledgeLabelLaboratoriesLesionLife ExpectancyLigandsLipopolysaccharidesLocationMolecularMorbidity - disease rateMusNatureNeurologicOligonucleotidesOperative Surgical ProceduresOutcomePathogenesisPathway interactionsPatientsProceduresProcessQuality of lifeRadiationReceptor SignalingRelative (related person)RiskRoleSignal PathwaySignal TransductionStimulusStrokeTLR4 geneTLR7 geneTNF geneTestingTherapeuticToll-like receptorsTranslationsUnited StatesWorkcytokinedisabilityheart valve replacementhigh riskimprovedmembermortalityneuroprotectionnovelpathogenpatient populationpreconditioningprophylacticreceptorrepairedresponseresponse to injurystroke therapysubcutaneous
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海外基金