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Molecular signatures of HNSCC in response to targeted therapies

Molecular signatures of HNSCC in response to targeted therapies
HNSCC 响应靶向治疗的分子特征
批准号：
8204526
负责人：
CHRISTINE H CHUNG
金额：
$38.94万
依托单位：
JOHNS HOPKINS UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
项目状态：
已结题
起止时间：
2007-07-20 至 2013-05-31
来源：
https://reporter.nih.gov/project-details/8204526
关键词：
AftercareAntibodiesAutomobile DrivingBiological MarkersBiological ModelsCell LineCell modelCellsCetuximabClinicClinicalClone CellsCollectionCombined Modality TherapyDNA Microarray ChipDataDiseaseEGFR Protein OverexpressionEpidermal Growth Factor ReceptorEpidermal Growth Factor Receptor Tyrosine Kinase InhibitorEventGene ExpressionGene Expression ProfileGenesGrowthHead and Neck Squamous Cell CarcinomaHeterogeneityImmunohistochemistryIn VitroIndividualInhibition of ApoptosisInstitutional Review BoardsLigand BindingLigandsMalignant Epithelial CellMolecularMolecular ProfilingMultivariate AnalysisMutationNeoplasmsOncogenicPathologyPathway interactionsPatient SelectionPatientsPhospho-Specific AntibodiesPrimary NeoplasmProcessPropertyProteinsProtocols documentationRNA InterferenceReceptor ActivationReceptor InhibitionReceptor SignalingRecurrenceRecurrent tumorResearch PersonnelResistanceResource SharingSystemTestingTransfectionTranslatingTumor TissueVariantWestern Blottingbasec-erbB-1 Proto-Oncogenescancer therapycohorthuman tissueimprovedin vitro Assayin vivokeratinocytenoveloverexpressionprognosticprogramsreceptorreceptor expressionresistance mechanismresponsesuccesstreatment responsetumor

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期刊论文(5)
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科研奖励(0)
会议论文
Loss of Trop2 promotes carcinogenesis and features of epithelial to mesenchymal transition in squamous cell carcinoma.
DOI： 10.1158/1541-7786.mcr-11-0241
发表时间： 2011-12
期刊： Molecular cancer research : MCR
影响因子： --
作者： [Wang J, Zhang K, Grabowska D, Li A, Dong Y, Day R, Humphrey P, Lewis J, Kladney RD, Arbeit JM, Weber JD, Chung CH, Michel LS]
通讯作者： Michel LS
Insulin-like growth factor-1 receptor inhibitor, AMG-479, in cetuximab-refractory head and neck squamous cell carcinoma.
DOI： 10.1002/hed.21478
发表时间： 2011-12
期刊： HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
影响因子： 2.9
作者： [Chung, Christine H., Pohlmann, Paula R., Rothenberg, Mace L., Burkey, Brian B., Parker, Joel, Palka, Kevin, Aulino, Joseph, Puzanov, Igor, Murphy, Barbara]
通讯作者： Murphy, Barbara
Decoding tobacco-related oral cancer ecosystem by integrative approach
  • 批准号：
    10733337
  • 项目类别：
  • 资助金额：
    $46.28万
  • 财政年份：
    2022
  • 负责人：
    CHRISTINE H CHUNG
  • 依托单位：
    UNIVERSITY OF UTAH
Decoding tobacco-related oral cancer ecosystem by integrative approach
  • 批准号：
    10677015
  • 项目类别：
  • 资助金额：
    $45.71万
  • 财政年份：
    2022
  • 负责人：
    CHRISTINE H CHUNG
  • 依托单位：
    UNIVERSITY OF UTAH
Decoding tobacco-related oral cancer ecosystem by integrative approach
Decoding tobacco-related oral cancer ecosystem by integrative approach
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