TRAINING IN THE MOLECULAR BIOLOGY OF NEURODEGENERATION

描述(由申请人提供)：我们建议继续一个非常成功的跨部门和跨机构的神经退化分子生物学培训计划-该计划致力于培训博士后和博士后学生在大学和与健康相关的研究实验室作为独立研究科学家的职业生涯。培训师都是哈佛大学的教职员工，他们对阿尔茨海默氏症和其他与衰老有关的神经退行性疾病进行了积极的研究。他们来自哈佛医学院和六家附属研究医院：贝丝以色列女执事医疗中心、布里格姆妇女医院、儿童医院、达纳-法伯癌症研究所、马萨诸塞州综合医院和麦克莱恩医院。该计划的教职员工包括分子生物学家、遗传学家、细胞生物学家、神经病理学家和生物化学家，为年龄相关的神经变性问题带来了广泛的经验和实验方法。博士前学生是从哈佛医学院授予学位的神经科学项目的研究生中招募和挑选出来的。博士后学生是从该项目的个别教员提名的申请者中挑选出来的。共有6名博士前实习生和8名博士后实习生被提议用于27名在年龄相关神经变性的基础和应用研究方面经验丰富的初级培训教师。在所有情况下，成功候选人的主要标准是对衰老和神经退行性研究的敬业精神和兴趣，以及在之前的培训中取得的最高水平的学术成就。所有学生都被要求参加专门的神经变性课程和研讨会。该计划的目的是建立一个框架，在这个框架内，可以对致力于衰老和神经退化问题的未来研究人员进行最佳培训，并可以改善和扩大该计划教职员工之间已经很好的关系。

DESCRIPTION (provided by applicant): We propose to continue a highly successful inter-departmental and inter-institutional Training Program in the Molecular Biology of Neurodegeneration - a program devoted to the training of pre- and postdoctoral students for careers as independent research scientists in universities and health- related research laboratories. The trainers are all Harvard faculty members with active research programs in Alzheimer's disease and other neurodegenerative disorders related to aging. They are drawn from the Harvard Medical School and six affiliated research hospitals: Beth Israel- Deaconess Medical Center, Brigham and Women's Hospital, Children's Hospital, Dana-Farber Cancer Institute, Massachusetts General Hospital, and McLean Hospital. Bringing a wide range of experience and experimental approaches to the problems of age-related neurodegeneration, the Program faculty includes molecular biologists, geneticists, cell biologists, neuropathologists, and biochemists. The predoctoral students are recruited into and drawn from the graduate students in the degree- granting Neuroscience Program of the Harvard Medical School. The postdoctoral students are chosen from among applicants nominated by individual faculty members of the Program. A total of six predoctoral trainees and eight postdoctoral trainees are proposed for a primary training faculty of 27 individuals experienced in basic and applied studies of age-related neurodegeneration. In all cases, the main criteria for successful candidates is dedication and interest in aging and neurodegeneration research and the highest level of academic achievement in their previous training. All students are required to participate in special neurodegeneration courses and seminars. The purpose of the Program is to create a framework within which the best training of future researchers devoted to problems in aging and neurodegeneration can take place and the already good relations among the Program faculty can be improved and extended.