Taut Bands in Myofascial Pain
肌筋膜疼痛中的绷紧带
基本信息
- 批准号:8122293
- 负责人:
- 金额:$ 23.42万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2010
- 资助国家:美国
- 起止时间:2010-09-01 至 2013-05-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAffectAftercareAgreementAreaAttentionBiochemicalBiomechanicsBreastCharacteristicsClinicalCommunitiesConsensusControl GroupsDevelopmentDiagnosisEtiologyFatigueFutureGoalsHigh PrevalenceHourImageIndividualLiverLocationMagnetic Resonance ElastographyManualsMeasurementMeasuresMechanicsMethodsMotionMuscleMuscle HypertoniaMyalgiaMyofascial Pain SyndromesMyofascial Trigger PointNatureOutcomeOutcome MeasurePainPalpationPatternPhysical ExaminationPhysiciansPropertyPublished CommentRecording of previous eventsResearchResearch PersonnelSymptomsSyndromeTechniquesTestingTimeTissuesVisual Analogue Pain ScaleWorkbaseimprovedin vivopressurepublic health relevancesoft tissuesuccesstrapezius muscletreatment effecttrigger point
项目摘要
DESCRIPTION (provided by applicant): Our preliminary study has, for the first time, imaged myofascial taut bands based on their stiffness values. This was accomplished using the Magnetic Resonance Elastography (MRE) technique. The goal of this application is to further test our hypothesis that MRE stiffness measurements of myofascial taut bands are reliable and sensitive to changes resulting from myofascial manual therapies. If the MRE technique is reliable and sensitive, it can be used to assess the efficacy of manual therapies in future studies. The current study will address the following specific aims: Specific Aim 1: To determine the reliability of MRE stiffness measurements of myofascial taut bands and their surrounding muscle tissue. Forty subjects with upper trapezius myofascial pain (as determined by clinical examination and history) and at least one taut band on MRE will be studied. An initial MRE examination will characterize the myofascial taut bands (location of the taut band in the MRE stiffness image, area of the taut band, and stiffness ratio between the taut band and the surrounding muscle tissue). Subjects will undergo a second MRE examination two hours later and the measures statistically compared to determine reliability. Pain will be quantified with an electroalgometer and pain VAS score before and after the second MRE; the change scores from this Aim will be used as a control group in Aim 2. Specific Aim 2: To determine the sensitivity of MRE stiffness measurements to change in a pain visual analog scale (VAS) as a result of Trigger-point Pressure Release therapy. Forty subjects with upper trapezius myofascial pain will be assessed using MRE. The overall muscle stiffness of the upper trapezius as well as the mechanical characterization of taut bands identified in MRE images (size and location of the taut band area and stiffness ratio) will be quantified. Tenderness will be evaluated by a physician using an electroalgometer and a pain VAS scale. Subjects will then be treated with a single treatment with TPR therapy. Pain will be reevaluated by the same individual and stiffness of the upper trapezius will be again measured with a second MRE. To test our hypothesis (that MRE taut band measurements are sensitive to changes resulting from therapy, as indicated by reduced pain score), associations between changes in pain VAS and changes in the MRE parameters of the taut bands will be statistically determined.
PUBLIC HEALTH RELEVANCE: Myofascial pain syndrome is a painful and often disabling condition. The exact benefits of manual therapies for myofascial pain remain unknown largely because there are no proven methods of detecting and measuring stiff, painful areas in muscles. Magnetic Resonance Elastography is able to image and measure muscle stiffness and therefore is a promising technique to accurately detect changes in stiff taut bands and trigger points after manual therapy treatment.
描述(由申请人提供):我们的初步研究首次根据肌筋膜绷紧带的刚度值对其进行成像。这是使用磁共振弹性成像(MRE)技术完成的。本申请的目的是进一步检验我们的假设,即肌筋膜拉紧带的MRE刚度测量结果对肌筋膜手动治疗引起的变化是可靠和敏感的。如果MRE技术是可靠和敏感的,它可以用来评估在未来的研究中的手动治疗的疗效。目前的研究将解决以下具体目标:具体目标1:确定MRE刚度测量的可靠性肌筋膜拉紧带及其周围的肌肉组织。将研究40名患有上睑肌肌筋膜疼痛(根据临床检查和病史确定)且MRE上至少有一条拉紧带的受试者。初步MRE检查将表征肌筋膜拉紧带(MRE刚度图像中拉紧带的位置、拉紧带的面积以及拉紧带与周围肌肉组织之间的刚度比)。受试者将在两小时后接受第二次MRE检查,并对测量结果进行统计学比较以确定可靠性。在第二次MRE之前和之后,将使用电测痛计和疼痛VAS评分对疼痛进行量化;该目标的变化评分将用作目标2中的对照组。具体目标二:确定MRE硬度测量值对触发点压力释放治疗导致的疼痛视觉模拟量表(VAS)变化的敏感性。将使用MRE评估40例患有上睑肌肌筋膜疼痛的受试者。将量化上睑肌的整体肌肉刚度以及MRE图像中识别的拉紧带的机械表征(拉紧带面积和刚度比的大小和位置)。将由医生使用电测痛计和疼痛VAS量表评价肌腱张力。然后,受试者将接受TPR单次治疗。疼痛将由同一个人重新评估,并将通过第二次MRE再次测量上肌僵硬度。为了检验我们的假设(MRE拉紧带测量对治疗引起的变化敏感,如疼痛评分降低所示),将统计确定疼痛VAS变化与拉紧带MRE参数变化之间的相关性。
公共卫生相关性:肌筋膜疼痛综合征是一种痛苦的,往往致残的条件。手动治疗肌筋膜疼痛的确切好处仍然未知,主要是因为没有经过验证的方法来检测和测量肌肉中僵硬,疼痛的区域。磁共振弹性成像能够成像和测量肌肉硬度,因此是一种有前途的技术,可以准确检测手动治疗后僵硬拉紧带和触发点的变化。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
KAI-NAN AN其他文献
KAI-NAN AN的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('KAI-NAN AN', 18)}}的其他基金
Extensibility of Rotator Cuff Muscle with Tendon Rupture Determined Using SWE
使用 SWE 确定肌腱断裂时肩袖肌肉的伸展性
- 批准号:
8616453 - 财政年份:2014
- 资助金额:
$ 23.42万 - 项目类别:
Automated Analysis of Lumbar Spine Kinematics from Dynamic Videofluoroscopy
通过动态视频透视自动分析腰椎运动学
- 批准号:
7301821 - 财政年份:2007
- 资助金额:
$ 23.42万 - 项目类别:
Automated Analysis of Lumbar Spine Kinematics from Dynamic Videofluoroscopy
通过动态视频透视自动分析腰椎运动学
- 批准号:
7470648 - 财政年份:2007
- 资助金额:
$ 23.42万 - 项目类别:
相似海外基金
How Does Particle Material Properties Insoluble and Partially Soluble Affect Sensory Perception Of Fat based Products
不溶性和部分可溶的颗粒材料特性如何影响脂肪基产品的感官知觉
- 批准号:
BB/Z514391/1 - 财政年份:2024
- 资助金额:
$ 23.42万 - 项目类别:
Training Grant
BRC-BIO: Establishing Astrangia poculata as a study system to understand how multi-partner symbiotic interactions affect pathogen response in cnidarians
BRC-BIO:建立 Astrangia poculata 作为研究系统,以了解多伙伴共生相互作用如何影响刺胞动物的病原体反应
- 批准号:
2312555 - 财政年份:2024
- 资助金额:
$ 23.42万 - 项目类别:
Standard Grant
RII Track-4:NSF: From the Ground Up to the Air Above Coastal Dunes: How Groundwater and Evaporation Affect the Mechanism of Wind Erosion
RII Track-4:NSF:从地面到沿海沙丘上方的空气:地下水和蒸发如何影响风蚀机制
- 批准号:
2327346 - 财政年份:2024
- 资助金额:
$ 23.42万 - 项目类别:
Standard Grant
Graduating in Austerity: Do Welfare Cuts Affect the Career Path of University Students?
紧缩毕业:福利削减会影响大学生的职业道路吗?
- 批准号:
ES/Z502595/1 - 财政年份:2024
- 资助金额:
$ 23.42万 - 项目类别:
Fellowship
感性個人差指標 Affect-X の構築とビスポークAIサービスの基盤確立
建立个人敏感度指数 Affect-X 并为定制人工智能服务奠定基础
- 批准号:
23K24936 - 财政年份:2024
- 资助金额:
$ 23.42万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Insecure lives and the policy disconnect: How multiple insecurities affect Levelling Up and what joined-up policy can do to help
不安全的生活和政策脱节:多种不安全因素如何影响升级以及联合政策可以提供哪些帮助
- 批准号:
ES/Z000149/1 - 财政年份:2024
- 资助金额:
$ 23.42万 - 项目类别:
Research Grant
How does metal binding affect the function of proteins targeted by a devastating pathogen of cereal crops?
金属结合如何影响谷类作物毁灭性病原体靶向的蛋白质的功能?
- 批准号:
2901648 - 财政年份:2024
- 资助金额:
$ 23.42万 - 项目类别:
Studentship
Investigating how double-negative T cells affect anti-leukemic and GvHD-inducing activities of conventional T cells
研究双阴性 T 细胞如何影响传统 T 细胞的抗白血病和 GvHD 诱导活性
- 批准号:
488039 - 财政年份:2023
- 资助金额:
$ 23.42万 - 项目类别:
Operating Grants
New Tendencies of French Film Theory: Representation, Body, Affect
法国电影理论新动向:再现、身体、情感
- 批准号:
23K00129 - 财政年份:2023
- 资助金额:
$ 23.42万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
The Protruding Void: Mystical Affect in Samuel Beckett's Prose
突出的虚空:塞缪尔·贝克特散文中的神秘影响
- 批准号:
2883985 - 财政年份:2023
- 资助金额:
$ 23.42万 - 项目类别:
Studentship