Multidisciplinary Research Training in Pulmonary Medicine

描述（由申请人提供）：本提案描述了我们在俄勒冈州健康与科学大学肺与重症监护医学部的研究培训计划。在这个程序中，我们提供最先进的，多学科的研究培训，在广泛的学科，包括细胞和分子生物学，整个器官病理生理学，以及基于人类的研究和流行病学研究。六名博士后研究员（主要是医学博士肺研究员）和两名研究生将分别获得两年研究培训的资金。研究将通过学员参加项目范围内的研究研讨会和期刊俱乐部来补充。我们相信，这样的项目范围内的会议和互动对于为年轻科学家提供他们自己项目之外的广泛研究视角至关重要，避免早期过度专业化和不适当的狭窄研究重点。课程工作也提供，包括研究的负责任行为的必修课程，以及适合学员从事研究生涯的广泛课程。这些包括药物学，实验设计，赠款写作，手稿写作，公开演讲和流行病学方法，并在我们的研究生课程和我们的人类调查计划中提供。研究导师是由经验丰富的科学家在培训年轻科学家的丰富经验的教师提供。大约一半的教师进行研究主要或主要涉及肺。其余的人在细胞和分子生物学方面有特定的专业领域，这些领域已经应用于肺部疾病的研究或很容易适用于它。该计划中实验室之间的互动和协同作用增加了丰富和广泛的培训环境。一个完善的定期跟踪学员进展的系统确保他们的持续发展，并在他们职业生涯的这个关键阶段扩大指导和建议的来源。这种方法将产生临床和基础研究人员，为学术医学和生物医学研究的挑战做好准备，并将有助于满足下一代科学家的需求。这些科学家将准备解决由哮喘、慢性支气管炎、肺气肿、急性呼吸窘迫综合征和其他肺部疾病日益加重的负担所引起的公共卫生问题。

Description (provided by applicant): This proposal describes our research training program in the Division of Pulmonary and Critical Care Medicine, Oregon Health & Science University. In this program, we offer state of the art, multidisciplinary research training in a wide range of disciplines including cell and molecular biology, whole organ pathophysiology, and both human based research and epidemiological research. Six post-doctoral fellows (primarily MD pulmonary fellows) and two graduate students will be offered funding for two years of research training each. Research will be supplemented by trainee participation in program wide research seminars and journal clubs. It is our belief that such program wide meetings and interactions are vital to providing young scientists with a broad perspective on research outside their own projects, avoiding early overspecialization and an inappropriately narrow research focus. Course work is also offered, and includes a mandatory course in Responsible Conduct of Research, as well as a wide range of courses appropriate to trainees embarking on a research career. These include statisics, experimental design, grant writing, manuscript writing, public speaking, and epidemiological methods, and are offered both in our graduate programs and in our Human Investigations Program. Research mentorship is provided by a faculty of seasoned scientists with extensive experience in training young scientists. About half the faculty conducts research primarily or principally involving the lung. The remainder have specific areas of expertise in cell and molecular biology that have either been applied to the study of lung disease or are easily applicable to it. Interactions and synergy among the laboratories in this program add to the rich and broad training environment. A well established system for regularly tracking the progress of trainees ensures their continued development, and broadens the sources of guidance and advice in this crucial stage of their careers. This approach will produce clinical and basic researchers prepared for the challenges of academic medicine and biomedical research, and will help fill the need in the next generation of scientists. These scientists will be prepared to address the public health issues raised by the increasing burden of asthma, chronic bronchitis, emphysema, acute respiratory distress syndrome, and other lung diseases.