MHIRT: Training Grant

描述（由申请人提供）：UCSC-MHIRT研究计划的长期目标是积极参与未被充分代表的少数民族学生与东道国的学生和教师合作，在自然和实验室环境中进行的长期国际生物医学相关研究项目。UCSC-MHIRT拥有悠久的研究生和本科生研究培训传统，提供具有挑战性和独特的生物研究机会，将丰富而刺激的文化体验与富有成效和创造性的科学研究职业培训相结合。这些经历为UCSC-MHIRT学生提供了更广阔的国际科学和教育视野，增强了自信和独立性，以及技术专业知识的实质性提高。我们的项目使少数族裔学生选择高级科学培训的人数有了令人满意的增长，从而成为下一代生物医学科学家和学术教师的领导。这项研究在五个主要的国外地点提供了广泛的令人兴奋的项目；巴塔哥尼亚、新西兰、德国、巴拿马和日本，范围从基础生物医学和流行病学调查到NCMHD使命宣言中包括的疾病病因学重点研究。这些包括：1)病态肥胖和相关疾病，如糖尿病、心血管疾病和肾功能不全；2)由营养不良或饥饿引起的幼儿发育病理；3)疾病从野生迁徙物种（如海洋哺乳动物和鸟类）向人类和其他一些地区的转移。UCSC-MHIRT项目不仅将为这些重要的研究做出直接的科学贡献，而且还将为MHIRT学生提供在生物医学相关领域的特殊科学培训。最近，从我们的长期研究中获得的结果为一些严重的人类病理提供了重要的临床见解，这些疾病不成比例地影响着美国少数民族和环太平洋地区的新兴国家。

DESCRIPTION (provided by applicant): The long term objective of the UCSC-MHIRT Research Program is to actively engage underrepresented minority students in on-going, long term international, biomedically relevant research projects conducted in both the natural and laboratory environment in collaboration with students and faculty from the host country. With a long tradition of both graduate and undergraduate research training, UCSC-MHIRT offers challenging and unique biological research opportunities that combine rich and stimulating cultural experience with productive and creative scientific research career training. These experiences provide UCSC-MHIRT students with broader international scientific and educational perspectives, increased self-confidence and independence, plus substantial improvements in technical expertise. Our program has produced a satisfying increase in the number of underrepresented minority students choosing advanced scientific training and consequently the leadership of the next generation of biomedical scientists and academic faculty. The research provides a broad spectrum of exciting projects in five major foreign sites; Patagonia, New Zealand, Germany, Panama and Japan ranging from basic biomedical and epidemiological investigation to focused research on disease etiology included in the NCMHD mission statement. These include: 1) morbid obesity and related conditions such as diabetes, cardiovascular disease and renal insufficiency; 2) early childhood developmental pathologies resulting from malnutrition or starvation; and 3) disease transfer from wild migratory species (e.g., marine mammals and birds) to humans and several other areas. The UCSC-MHIRT program will not only make direct scientific contributions to these vital studies but will do so while providing MHIRT students with exceptional scientific training in fields of immediate biomedical relevance. Recently, results obtained from our long term studies have provided important clinical insights into several severe human pathologies that disproportionately impact U.S. minority populations and emerging countries of the Pacific Rim. RELEVANCE: The UCSC-MHIRT program is designed to provide highly quality research-training for underrepresented and minority students to foster their pursuit of advanced academic scientific training and professional careers in biomedical research. The program offers research opportunities with strong emphasis in basic biomedical science with emphasis on pathologies that disproportionately impact minority populations worldwide.