NEBRASKA CENTER FOR NANOMEDICINE ADMINISTRATIVE CORE

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 内布拉斯加州纳米医学中心（NCN），生物医学研究卓越中心（COBRE）已从该奖项创建。纳米医学是生物医学研究的一个快速发展的领域，它使用纳米尺寸的设备来解决改善药物和基因递送的迫切需求。这种“下一代”疗法可以特异性地将药物和重组DNA递送到疾病的焦点区域或肿瘤，以最大化临床益处，同时限制不良副作用。这种纳米技术有望通过生物成像技术大大改善早期诊断。这与美国国立卫生研究院（NIH）的路线图相似，在该研究院，纳米医学被确定为未来十年的发展计划。为了与这些想法保持一致，该中心将致力于将生物医学和材料科学研究领域已经强大的领域加入到一个更强大的单位中。这些目标现在可以通过内布拉斯加大学医学中心（UNMC）内生物医学科学（神经科学，病理学，免疫学，药理学，免疫和癌症生物学）和材料科学（纳米材料，聚合物，药物输送和基因输送）的既定专业知识来实现。该中心的主要目标是为协同研究活动提供基础，并将这些努力转化为治疗方案有限的疾病的临床效益，同时开发一个潜在的“有远见”的科学领域，内布拉斯加州可以成为世界领导者。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Nebraska Center for Nanomedicine (NCN), a Center of Biomedical Research Excellence (COBRE) has been created from this award. Nanomedicine is a rapidly developing area of biomedical research that uses devices of nanoscale size to address urgent needs for improved drug and gene delivery. Such "next generation" therapies can specifically deliver drugs and recombinant DNAs to focal areas of disease or to tumors to maximize clinical benefit while limiting untoward side effects. Such nanotechnologies are expected to drastically improve early diagnosis through bioimaging techniques. This parallels the road map for the National Institutes of Health (NIH) where nanomedicine was identified as a development initiative for the next decade. In keeping with these ideas, the Center will serve to join already strong areas of biomedical and material science research into an even stronger unit. Such goals can now be realized with the established expertise in biomedical sciences (neuroscience, pathology, immunology, pharmacology, immunization and cancer biology) and those in the material sciences (nanomaterials, polymers, drug delivery, and gene delivery) within the University of Nebraska Medical Center (UNMC). The primary goal of the Center is to provide a foundation for synergistic research activities and translating the efforts into clinical benefit for diseases with limited treatment options while simultaneously developing a potentially "visionary" area of science where the State of Nebraska can emerge as a world-leader.