Long-Term Complications of Children/Adolescents & Cancer

描述(申请人提供)：我们建议于2008年6月6-7日在加拿大安大略省尼亚加拉湖畔的皇后码头酒店举办为期两天的会议。儿科血液学家/肿瘤学家、儿科护士从业者、儿科心理学家、儿科肿瘤学社会工作者、内科肿瘤学家、研究员、住院医生、实习生、临床研究助理和其他初级保健提供者将对该计划感兴趣。将讨论儿童和青少年癌症治疗后的生育和生殖问题。 第十届儿童和青少年癌症治疗长期并发症国际会议的目标是：1)回顾正常的睾丸功能和精子发生；2)回顾男性性腺的毒性；3)回顾男性生殖细胞移植的实验；4)回顾卵巢功能的正常和卵巢储备的评估；5)回顾急性和早产性卵巢衰竭；6)回顾实验性的女性生育能力保存；7)回顾男性生育能力保存的设施和技术；8)回顾女性生殖细胞移植和胚胎保存的临床应用；9)回顾患者对男性和女性生育能力保存的态度；10)回顾有关儿童和青少年生育力保存的伦理问题。会议将包括国家和国际公认的这些领域专家的发言。 这次会议将促进儿童癌症幸存者研究的研究人员与外国研究人员之间的互动，其中许多人参加了这次会议。会议将促进介绍和讨论与生育和生殖专题有关的研究成果，以及儿童癌症治疗的后期影响这一更广泛的专题。在非正式讨论期间，与会者将制定假说和初步研究战略，以便在会议结束后与他们的研究伙伴进一步扩大。

DESCRIPTION (provided by applicant): We propose to hold a two-day conference on June 6 - 7, 2008 at Queen's Landing Inn (Niagara-on-the-Lake, Ontario, Canada). The program will be of interest to pediatric hematologists/oncologists, pediatric nurse practitioners, pediatric psychologists, pediatric oncology social workers, medical oncologists, fellows, residents, interns, clinical research associates and other primary care providers. The topic of fertility and reproduction following treatment of children and adolescents for cancer will be addressed. The goals of the 10th International Conference on Long-Term Complications of Treatment of Children and Adolescents for Cancer will be to: 1) review normal testicular function and spermatogenesis; 2) review experimental male gonadal toxicity; 3) review experimental male germ cell transplantation; 4) review normal ovarian function and assessment of ovarian reserve; 5) review acute and premature ovarian failure; 6) review experimental female fertility preservation; 7) review facilities and techniques for male fertility preservation; 8) review clinical female germ cell transplantation and embryo preservation; 9) review patient attitudes toward male and female fertility preservation; 10) review ethical issues regarding fertility preservation in children and adolescents. The conference will include presentations by nationally and internationally recognized experts in these areas. The conference will facilitate interactions among the investigators of the Childhood Cancer Survivor Study, many of whom attend this conference, and foreign investigators. The conference will facilitate the presentation and discussion of research results, both pertaining to the topic of fertility and reproduction, as well as the broader topic of late effects of treatment of childhood cancer. The attendees at the conference, during informal discussions, will develop hypotheses and preliminary research strategies to be further expanded with their research partners following completion of the conference.