Long-Term Complications of Children/Adolescents & Cancer

描述（由申请人提供）：我们建议于2008年6月6日至7日在皇后兰丁酒店（尼亚加拉湖，安大略，加拿大）举行为期两天的会议。该计划将感兴趣的儿科血液学家/肿瘤学家，儿科护士执业者，儿科心理学家，儿科肿瘤社会工作者，医学肿瘤学家，研究员，居民，实习生，临床研究助理和其他初级保健提供者。将讨论儿童和青少年癌症治疗后的生育力和生殖问题。 第10届儿童和青少年癌症治疗长期并发症国际会议的目标是：1）审查正常睾丸功能和精子发生; 2）审查实验性男性性腺毒性; 3）审查实验性男性生殖细胞移植; 4）审查正常卵巢功能和卵巢储备评估; 5）审查急性和过早卵巢衰竭; 6）审查实验性女性生育力保存; 7）审查男性生育力保存的设施和技术; 8）审查临床女性生殖细胞移植和胚胎保存; 9）审查患者对男性和女性生育力保存的态度; 10）审查儿童和青少年生育力保存的伦理问题。会议将包括这些领域的国内和国际知名专家的发言。 会议将促进儿童癌症幸存者研究的研究人员之间的互动，其中许多人参加了这次会议，以及外国研究人员。会议将促进研究成果的介绍和讨论，既涉及生育和生殖的主题，也涉及儿童癌症治疗的晚期效应的更广泛的主题。在非正式讨论期间，与会者将制定假设和初步研究战略，以便在会议结束后与他们的研究伙伴进一步扩大。

DESCRIPTION (provided by applicant): We propose to hold a two-day conference on June 6 - 7, 2008 at Queen's Landing Inn (Niagara-on-the-Lake, Ontario, Canada). The program will be of interest to pediatric hematologists/oncologists, pediatric nurse practitioners, pediatric psychologists, pediatric oncology social workers, medical oncologists, fellows, residents, interns, clinical research associates and other primary care providers. The topic of fertility and reproduction following treatment of children and adolescents for cancer will be addressed. The goals of the 10th International Conference on Long-Term Complications of Treatment of Children and Adolescents for Cancer will be to: 1) review normal testicular function and spermatogenesis; 2) review experimental male gonadal toxicity; 3) review experimental male germ cell transplantation; 4) review normal ovarian function and assessment of ovarian reserve; 5) review acute and premature ovarian failure; 6) review experimental female fertility preservation; 7) review facilities and techniques for male fertility preservation; 8) review clinical female germ cell transplantation and embryo preservation; 9) review patient attitudes toward male and female fertility preservation; 10) review ethical issues regarding fertility preservation in children and adolescents. The conference will include presentations by nationally and internationally recognized experts in these areas. The conference will facilitate interactions among the investigators of the Childhood Cancer Survivor Study, many of whom attend this conference, and foreign investigators. The conference will facilitate the presentation and discussion of research results, both pertaining to the topic of fertility and reproduction, as well as the broader topic of late effects of treatment of childhood cancer. The attendees at the conference, during informal discussions, will develop hypotheses and preliminary research strategies to be further expanded with their research partners following completion of the conference.