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Replication checkpoint activation and silencing

Replication checkpoint activation and silencing
复制检查点激活和静默
批准号：
8197569
负责人：
MATTHEW MICHAEL
金额：
$31.76万
依托单位：
UNIVERSITY OF SOUTHERN CALIFORNIA
依托单位国家：
美国
项目类别：
财政年份：
2003
资助国家：
美国
项目状态：
已结题
起止时间：
2003-05-01 至 2013-01-31
来源：
https://reporter.nih.gov/project-details/8197569
关键词：
ATM activationATR protein kinaseAntineoplastic AgentsAttenuatedBiochemicalBiochemical GeneticsBiological AssayBypassCaenorhabditis elegansCancer EtiologyCell Cycle CheckpointCell Division ProcessCellsChromosomal BreaksChromosomal translocationChromosome BreakageChromosomesComplexDNADNA DamageDNA Polymerase IDNA biosynthesisDNA-Directed DNA PolymeraseEmbryoEventGeneticGenetic MaterialsGenetic ScreeningGenome StabilityGoalsHumanLaboratoriesLeadLeftLesionMaintenanceMediatingMolecularNormal CellOrthologous GenePathway interactionsPhysiologicalPlayPolymeraseProcessProtein KinaseProteinsRad30 proteinRecruitment ActivityRegulationReplication-Associated ProcessRoleS PhaseSignal PathwaySignal TransductionSiteStressSystemXenopusbasecancer cellchromosome replicationegggenetic analysismeetingsnovelpublic health relevancerepairedresponseubiquitin ligaseubiquitin-protein ligase

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