Informatics

信息学

• 批准号: 8084109
• 负责人: Jack W. London
• 金额: $ 20.1万
• 依托单位: THOMAS JEFFERSON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-03 至 2013-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8084109
• 关键词: Adoption; Adverse event; Basic Science; Cancer Center; Capital; Clinical; Clinical Research; Clinical Trials; Collaborations; Community Outreach; Computer software; Computers; Consult; Consultations; Data; Data Files; Data Set; Databases; Development; Funding; Genomics; High Performance Computing; Hospitals; Informatics; London; Malignant Neoplasms; Mission; NCI Center for Cancer Research; Names; Online Systems; Participant; Pathology; Reporting; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Proposals; Resource Informatics; Resource Sharing; Resources; Retrieval; Services; Software Tools; Specimen; System; Tissue Banking; Tissue Banks; Translational Research; Universities; Work; anticancer research; cancer Biomedical Informatics Grid; computerized data processing; data management; data sharing; design; informatics shared resource; interoperability; member; outreach program; programs; repository; software development; tool; working group

INFORMATICS SHARED RESOURCE The Informatics Shared Resource (ISR) supports for the cancer center's basic, clinical, and translational research. Formerly known as the Shared Computer Facility, this shared resource's name change reflects the shift in focus of the facility from providing central computing hardware platforms for investigators, to providing services for management and processing of data and information. These services include creating research software, data file management, hardware and software acquisition, and computer-related consultation. The ISR has supported cancer center research by developing web-based database applications for clinical trials, biospecimen research repositories, and various research projects. It provides management of very large genomic experimental data sets, acquisition of hardware, development of software tools to facilitate inter- and intra-institutional collaborative research programs, and assistance with design proposals for research-related computing. The clinical trials applications provide information on available clinical trials, the registration of participants on these trials, and the fully automated reporting of trial adverse events. The biospecimen repository applications provide investigators with information characterizing specimens available for research. Applications and strategies for the storage and retrieval of microarray experimental results were developed. Video conferencing systems were acquired and webbased document sharing applications developed for geographically dispersed research collaborations. Informatics Shared Resource staff consult with investigators to recommend hardware and software, ranging from the desktop units to high performance computing clusters. Recognizing the importance for interoperability of independently developed informatics systems as crucial to the furtherance of cancer research through the sharing of research data and resources, the ISR has been an active participant in the NCI's cancer Biomedical Informatics Grid (caBIG¿) since the initiative's inception. This resource has been a funded developer and/or adopter in the Integrated Cancer Research and Tissue Bank and Pathology Tools Workspaces. KCC is among the first cancer centers to deploy caBIG¿ tools. The shared resource director, Dr. London, is a member of the Data Sharing and Intellectual Capital Work Group. Staff members have served as unfunded participants in the Clinical Trials Management Systems Work Space, to keep abreast of developments in this group for possible adoption at the center. The ISR also supports cancer center programs which relate to research, such as the clinical trials applications, seminar conferencing services and the database application for tracking seminars. These are made available to Jefferson Cancer Network hospitals and cancer center community outreach programs, such as the Buddy Program.

信息学共享资源 信息学共享资源（ISR）支持癌症中心的基础、临床和翻译 research.以前称为共享计算机设施，这个共享资源的名称变化反映了 该设施的重点从为调查人员提供中央计算硬件平台， 为数据和信息的管理和处理提供服务。这些服务包括创建 研究软件、数据文件管理、硬件和软件采购以及计算机相关 协商ISR通过开发基于网络的数据库支持癌症中心的研究 用于临床试验、生物样本研究库和各种研究项目的应用。它提供 管理非常大的基因组实验数据集，获取硬件，开发 软件工具，以促进机构间和机构内的合作研究计划，并协助 研究相关计算的设计方案。临床试验申请提供以下信息： 可用的临床试验，这些试验的参与者登记，以及完全自动化的报告， 试验不良事件。生物样本存储库应用程序为研究人员提供信息 鉴定可供研究的标本。数据存储和检索的应用和策略 开发了微阵列实验结果。购置了网络视频会议系统 为地理上分散的研究合作开发的文档共享应用程序。 信息学共享资源工作人员与调查人员协商，以推荐硬件和软件， 从桌面单元到高性能计算集群。认识到 独立开发的信息系统的互操作性对促进癌症的发展至关重要 通过共享研究数据和资源，ISR一直积极参与 NCI的癌症生物医学信息网格（caBIG）自该倡议成立以来。该资源已 在综合癌症研究和组织库和病理学的资助开发者和/或采用者 工具工作区。KCC是第一批部署caBIG工具的癌症中心之一。共享资源 董事伦敦博士是数据共享和知识资本工作组的成员。工作人员 作为临床试验管理系统工作空间的无资金参与者， 了解这一群体的发展情况，以便在中心采用。ISR也支持癌症 与研究相关的中心计划，如临床试验申请，研讨会会议 服务和跟踪研讨会的数据库应用程序。这些都是提供给杰斐逊癌症 网络医院和癌症中心社区外展计划，如伙伴计划。