P30 Center in Craniofacial Bone Biology

P30 颅面骨生物学中心

• 批准号: 7934062
• 负责人: Nicola C Partridge
• 金额: $ 74.54万
• 依托单位: NEW YORK UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-17 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7934062
• 关键词: P30; Center; Craniofacial; Bone; Biology

DESCRIPTION (provided by applicant): This is a P30 application to establish a Center in Craniofacial Bone Biology at New York University College of Dentistry (NYUCD). The PI, Dr. Nicola C. Partridge, has just been recruited as the new Chair of Basic Science and Craniofacial Biology at NYUCD with the agenda of consolidating and expanding Bone Biology at NYUCD. She is an internationally renowned, established bone biologist. A number of existing faculty members at the College of Dentistry have a significant focus on bone and cartilage growth, biomineralization and biomaterials. Dr. Partridge brings tremendous experience and stature in a number of areas of bone biology such as osteoblast differentiation, matrix metalloproteinases, parathyroid hormone action, transcription, electromagnetic stimulation of osteoblasts, chemokines and osteoclasts, as well as administrative and mentoring skills, which will pull the group together into a cohesive entity. Together with the existing faculty, Dr. Partridge will recruit two new junior basic science faculty in bone biology. They will be recruited in osteoclast biology, and osteocytes and their interaction with bone matrix to complement Dr. Partridge's and the existing faculty members' areas of research. The new junior faculty will have at least 75% of their time dedicated to research. The funds of the P30 grant will be used to support this effort for two years and provide partial support for their start-up packages. The College of Dentistry will provide the remainder of their salaries and start-up funds during the period of the award and continue to support the faculty with total salary support and the remainder of their start-up packages for at least two additional years after the termination of the P30. The recruitment of Dr. Partridge and two junior faculty will permit the establishment of a strong interdisciplinary Craniofacial Bone Biology Center at NYUCD. PUBLIC HEALTH RELEVANCE: This is a P30 application to establish a Center in Craniofacial Bone Biology at New York University College of Dentistry (NYUCD). This will advance research into understanding important disease processes such as cleft palate and lead to strategies for the repair of such problems along with Craniofacial injuries caused by cancer, accident and war using regenerative medicine techniques.

描述（由申请人提供）：这是一份P30申请，旨在纽约大学牙科学院（NYUCD）建立颅面骨生物学中心。PI，Nicola C博士。Partial，刚刚被招募为基础科学和颅面生物学在NYUCD与巩固和扩大在NYUCD骨生物学的议程的新主席。她是一位国际知名的骨生物学家。牙科学院的一些现有教师对骨和软骨生长，生物矿化和生物材料有着重要的关注。Parliament博士在骨生物学的许多领域带来了巨大的经验和地位，如成骨细胞分化，基质金属蛋白酶，甲状旁腺激素作用，转录，成骨细胞，趋化因子和破骨细胞的电磁刺激，以及管理和指导技能，这将把小组拉到一起成为一个有凝聚力的实体。与现有的教师一起，Parkman博士将招募两名新的骨生物学初级基础科学教师。他们将在破骨细胞生物学，骨细胞及其与骨基质的相互作用，以补充博士招募Parkman的和现有的教师的研究领域。新的初级教师将有至少75%的时间用于研究。P30赠款的资金将用于支持这一努力两年，并为他们的启动包提供部分支持。牙科学院将在奖励期间提供剩余的工资和启动资金，并继续支持教师的总工资支持和他们的启动包的剩余部分至少在P30终止后的两年。Parliament博士和两名初级教师的招聘将允许在NYUCD建立一个强大的跨学科颅面骨生物学中心。 公共卫生相关性：这是一个P30应用程序，以建立一个中心，颅面骨生物学在纽约大学牙科学院（NYUCD）。这将促进研究了解重要的疾病过程，如腭裂，并导致修复这些问题的战略沿着与颅面损伤所造成的癌症，事故和战争使用再生医学技术。