Yoga for women with breast cancer undergoing radiotherapy

适合接受放射治疗的乳腺癌女性的瑜伽

• 批准号: 8041091
• 负责人: Lorenzo Cohen
• 金额: $ 24.82万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2016-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8041091
• 关键词: Acute; Address; Adherence; Adjuvant; Adverse effects; Aftercare; Anxiety; Appointment; Attention; Behavior; Breast Cancer Treatment; Breathing; Cancer Patient; Cessation of life; Cognitive; Combined Modality Therapy; Control Groups; Cost Effectiveness Analysis; Counseling; Diagnosis; Disease Progression; Distress; Emotional; Fatigue; Fright; Health; Health Care Costs; Home environment; Hospitals; Hydrocortisone; Individual; Intervention; Life; Lung; Maintenance; Malignant Neoplasms; Measures; Mediating; Meditation; Mental Depression; Mental Health; Morbidity - disease rate; Movement; Operative Surgical Procedures; Outcome; Participant; Patients; Periodicity; Phase III Clinical Trials; Physical Function; Physical activity; Physiological; Posture; Process; Productivity; Psychological Side Effects; Quality of life; Radiation; Radiation therapy; Randomized; Recovery; Recurrence; Relaxation; Relaxation Techniques; Reporting; Research; Schedule; Science; Skin; Sleep disturbances; Social support; Source; Spirituality; Stress; Stretching; Symptoms; Techniques; Telephone; Time; Trauma; Treatment Efficacy; Treatment Protocols; Woman; Work; Yoga; arm; behavior change; body-mind; cancer therapy; chemotherapy; coping; cost effectiveness; economic outcome; experience; follow-up; group intervention; improved; indexing; intervention effect; malignant breast neoplasm; preference; programs; psychologic; public health relevance; social; social model; standard of care; stress management; stressor; treatment as usual; treatment effect; treatment planning; visual imagery

DESCRIPTION (provided by applicant): Cancer and its treatment are associated with considerable distress, impaired quality of life (QOL), poor mental health, and reduced physical function. This is particularly true for women with breast cancer who receive multimodal treatment over an extended period of time. Many women undergo surgery and chemotherapy, which are often followed by radiotherapy. It is important to develop programs that can help ameliorate the treatment-related morbidity that accumulates over time for women with breast cancer. Furthermore, given the stressful time demands posed by radiotherapy treatment (patients typically receive treatment 5-days per week for 6 weeks) it is crucial that programs be easily incorporated into the treatment schedule. Research suggests that stress-reduction programs tailored to the cancer setting may help patients cope with the acute effects of treatment and improve QOL after treatment. Yoga, an ancient Indian science, incorporates stress-reduction techniques including regulated breathing, visual imagery, meditation, and various gentle stretching postures. Yoga may be particularly useful for women with breast cancer after surgery and while undergoing radiation treatment because of the stress management and relaxation techniques and the gentle stretching that should facilitate recovery. Preliminary studies found yoga is useful for women with breast cancer undergoing radiotherapy. Integrating a yoga program into the treatment regimen of women undergoing radiotherapy for breast cancer makes participation in the program easy and compliance has been high. We will determine the efficacy of implementing a yoga program for patients with breast cancer as an adjuvant to their radiotherapy. Patients with breast cancer who are undergoing radiotherapy will be randomly assigned to one of three groups: a yoga group, a stretching/relaxation group, or a waitlist control group. Participants in the two intervention groups will attend sessions 3 days/week throughout their 6-week radiotherapy schedule. Measures will be obtained prior to randomization, midway through radiotherapy, during the last week of radiotherapy, and 1 and 3, 6 and 12 months after the end of radiotherapy. We will examine indices of QOL, fatigue, sleep disturbances, mental health, cost- effectiveness analysis, work and/or home productivity, and cortisol rhythmicity. We hypothesize that the yoga program will help facilitate recovery and alleviate the physiological and psychological side effects experienced by patients who are currently receiving radiotherapy. PUBLIC HEALTH RELEVANCE: The proposed study will examine efficacy of incorporating a Yoga program alongside radiotherapy for women with breast cancer. If we find that the Yoga program facilitates recovery and alleviates the psychological and physiological side effects experienced by women undergoing radiotherapy, then this type of program can be incorporated into the treatment plan as the standard of care. Future research could examine individual preferences for different types of mind-body or physical activity programs incorporated in the treatment plan to help with recovery.

描述（由申请人提供）：