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The Role of beta-adrenergic Signaling in Prostate Cancer

The Role of beta-adrenergic Signaling in Prostate Cancer
β-肾上腺素能信号在前列腺癌中的作用
批准号：
8121262
负责人：
Jindan Yu
金额：
$24.9万
依托单位：
NORTHWESTERN UNIVERSITY AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
项目状态：
已结题
起止时间：
2008-09-01 至 2013-08-31
来源：
https://reporter.nih.gov/project-details/8121262
关键词：
ADRB2 geneAddressAdhesionsAdrenergic AgentsAmericanBenignBenign Prostatic HypertrophyBiological MarkersBreastCancer EtiologyCancer PrognosisCell DeathCell LineCell ProliferationCell physiologyCell-Cell AdhesionCellsCessation of lifeClinicalCollaborationsCuesCyclic AMPDataData ReportingDiagnosisDiseaseEnvironmentEnvironmental Risk FactorEpithelial CellsExhibitsG-Protein-Coupled ReceptorsGene ExpressionGene Expression ProfileGene Expression RegulationGene ProteinsGenesGeneticGenomeGoalsGrowthGrowth and Development functionHistone H3HormonesImmunohistochemistryIn VitroLaboratoriesLeadLesionLigand BindingLinkLocalized DiseaseLysineMalignant NeoplasmsMalignant neoplasm of lungMalignant neoplasm of prostateMediatingMediator of activation proteinMemoryMetastatic Prostate CancerMetastatic toMichiganMolecularMonitorNeoplasm MetastasisOncogenicOperative Surgical ProceduresOutcomePathway interactionsPatientsPatternPlayPolycombPositioning AttributePre-Clinical ModelProstateProteinsQualifyingRadiationRefractoryRegulationRepressionReproduction sporesResearch InfrastructureRoleSignal PathwaySignal TransductionSignaling MoleculeSolidSwitch GenesTechnologyTherapeutic InterventionTissue MicroarrayTumor Suppressor GenesTumor Suppressor ProteinsUniversitiesWorkadrenergicanticancer researchbeta-2 Adrenergic Receptorscell growthcell typecohortdensityeffective therapyexperiencefusion genegene functiongene repressionhistone methyltransferasehuman EZH2 proteinin vivoinnovationkidney cellmenmouse modelnext generationnoveloutcome forecastoverexpressionpre-clinicalprognosticsuccesstumortumor progressiontumorigenesis

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