Experimental Pathology

实验病理学

基本信息

批准号：
8038250
负责人：
KAM-MENG TCHOU-WONG
金额：
$ 17.89万
依托单位：
NEW YORK UNIVERSITY SCHOOL OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-03-01 至 2013-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8038250
关键词：
Administrative Coordination Anatomy Animal Model Animals Area Arts Basic Science Breast Cancer Center Support Grant Chest Clinical Clinical Pathology Clinical Research Collaborations Communities Contracts Dermatologist Disease Doctor of Philosophy Education Educational process of instructing Environmental Exposure Equipment Evaluation Experimental Animal Model Experimental Pathology Fees Histopathology Histopathology Facility Hospitals Human Human Resources Immunohistochemistry Individual Knowledge Laboratories Link Maintenance Medical Methodology Microscopic Microtomy Operating Rooms Organism Paraffin Paraffin Embedding Pathology Play Preparation Principal Investigator Process Prostate Provider Quality Control Research Research Activity Research Ethics Committees Research Infrastructure Research Personnel Research Support Resource Sharing Resources Retrieval Role Sampling Science Services Site Source Specimen Staging Staining method Stains Structure System Technology Thoracic Oncology Time Tissue Banking Tissue Banks Tissue Embedding Tissues Training Training Programs Training and Education Tumor Bank Work animal tissue base cost experience forest human tissue improved interest melanoma member neuro-oncology novel organizational structure repaired square foot tissue preparation tissue processing translational study tumor

项目摘要

The Experimental Pathology Shared Resource System brings together, under a single administrative structure, a variety of services requiring the technology and expertise of anatomic pathology. The overall objectives of the system are to provide quality-controlled, stable and cost-effective services for the microscopic analysis of human and animal tissues. It is divided into two functional units: 1) Tissue Acquisition and Banking Services (TABS) and 2) Histopathology. TABS coordinates sample acquisition, storage and retrieval services for relevant human tissues and is composed of five affiliated tissue banks (Breast, Prostate, Neuro-oncology, Thoracic, Melanoma). A central administrative core supplies infrastructure and IT support to link individual banks. The Histopathology Unit consists of three sub-cores, each with unique functions defined by the needs of local investigators. The Sterling Forest Research Histopathology Core (RHC) offers large-volume, high-throughput services for the animal carcihogenesis studies conducted by researchers on that campus, whereas the Manhattan RHC focuses on training and customized services for the disparate needs of the numerous Manhattan-based labs. The Immunohistochemistry sub-Core (IHC), located next to the Clinical Pathology labs in Bellevue Hospital, provides basic tissue processing of human specimens as weir as immunohistochemical services for both human and animal studies. Administrative integration allows the seamless exchange of samples and expertise between functional components, without sacrificing the unique benefits afforded by each sub-core. It also facilitates the directed "match-making" of investigators from different departments, thus promoting the collaborative synergies necessary for novel translational studies. Together, Experimental Pathology subcores support the research of almost 100 investigators.

实验病理共享资源系统在单个管理下汇集在一起结构，各种服务，需要解剖病理学的技术和专业知识。总体该系统的目标是为质量控制，稳定且具有成本效益的服务人类和动物组织的微观分析。它分为两个功能单元：1）组织收购和银行服务（TABS）和2）组织病理学。标签协调样本采集，相关人体组织的存储和检索服务，由五个关联组织库组成（乳房，前列腺，神经肿瘤学，胸腔，黑色素瘤）。中央行政核心用品基础架构及其支持单个银行的支持。组织病理学单元由三个子核组成，每个都有由当地研究人员的需求定义的独特功能。斯特林森林研究组织病理学核心（RHC）为动物癌发生提供了大量的高通量服务研究人员对该校园进行的研究，而曼哈顿RHC则专注于培训和定制服务，可满足众多基于曼哈顿实验室的不同需求。这免疫组织化学子核（IHC），位于贝尔维尤医院的临床病理实验室旁边，提供人类标本的基本组织加工作为堰，作为免疫组织化学服务人类和动物研究。行政整合允许无缝交换样本和功能组件之间的专业知识，而无需牺牲每个子核心带来的独特好处。它还促进了来自不同部门的调查人员的定向“匹配”，从而促进了新型翻译研究所需的协作协同作用。一起，实验病理亚核支持近100名调查人员的研究。