Experimental Animal Facility

实验动物和暴露核心设施的目标是提供高度专业化的 共享资源以支持纽约大学癌症相关癌症研究所成员的科学需求 致癌模型和致癌物给药的动物研究。该设施由两个 综合单位、动物护理和暴露股和吸入暴露股，后者提供 专门的动物护理，为啮齿动物物种实验提供技术援助，包括交付 致癌和有毒化学品、用于挑战实验的感染剂或干预化合物 通过各种暴露途径进行化学预防或化疗，包括吸入、全身、经皮、 和口服给药。此外，几种用于实验动物皮肤照射的辐射设备 对于电子，紫外线和X射线也是可用的。动物护理与暴露单元与吸入器 资源的曝光单元提供纽约大学学院在其他地方不能提供的独特服务 医学；事实上，吸入暴露室是同类设施中最大的学术设施之一。我们提供 在癌症相关动物研究和尸检服务的实验设计和实施方面的专业知识 动物实验。我们提供的另一项独特服务是隔离住房和健康监测 尚未证实无病毒抗体(VAF)状态的动物或携带可移植肿瘤的动物 尚未进行地图测试；使用这些类型的动物可以进行可行性或试验性研究 用这些动物做的小实验。通过提供全面的科学咨询和合作 在致癌动物模型和致癌物暴露方面，我们的主要目标是促进和增强 NYUCI研究人员之间的科学互动和生产力。此共享资源可供所有人使用 纽约大学癌症研究所的成员和纽约大学社区的其他成员，但癌症研究所 会员优先于非会员。

The objective of the Experimental Animal and Exposure Core Facility is to provide a highly specialized shared resource to support the scientific needs of members of the NYU Cancer Institute for cancer-related animal research in carcinogenesis models and in carcinogen administration. The facility consists of two ntegrated units, the Animal Care and Exposure Unit and the Inhalation Exposure Unit, which provides specialized animal care, technical assistance for experiments with rodent species involving delivery of carcinogenic and toxic chemicals, infectious agents for challenge experiments, or intervention compounds for chemoprevention or chemotherapy via various routes of exposure including inhalation, systemic, dermal, and oral administration. In addition, several radiation equipments for skin irradiation of laboratory animals with electrons, UV and X-ray are also available. The Animal Care and Exposure Unit and the Inhalation Exposure Unit of the resource provide unique services that are not offered elsewhere at NYU School of Medicine; in fact, the Inhalation Exposure Unit is one of the largest academic facilities of its kind. We provide expertise in experimental design and conduct for cancer-related animal studies and necropsy services for animal experiments. Another unique service we provide is segregated housing and health monitoring of animals that do not yet have a proven virus antibody-free (VAF) status or that carry transplantable tumors that have not yet been MAP tested; work with these types of animals allows feasibility or pilot studies and small experiments with these animals. By providing comprehensive scientific consultation and collaboration on carcinogenesis animal models and carcinogen exposure, our primary goal is to facilitate and enhance scientific interaction and productivity among NYUCI investigators. This shared resource is available to all members of the NYU Cancer Institute and other members of the NYU community, but Cancer Institute members have priority over nonmembers.