Experimental Animal Facility

实验动物和暴露核心设施的目标是提供高度专业化的 共享资源，以支持纽约大学癌症研究所成员的癌症相关的科学需求 在致癌模型和致癌物给药方面的动物研究。该设施包括两个 综合单位，动物护理和接触单位和吸入接触单位，提供 专门的动物护理，啮齿类动物实验的技术援助， 致癌和有毒化学品、用于激发实验的感染因子或干预化合物 用于化学预防或化学疗法，通过各种途径接触，包括吸入，全身，皮肤， 和口服给药。此外，还介绍了几种用于实验动物皮肤照射的辐射设备 紫外线和X射线也是可用的。动物护理和暴露单位和吸入 资源的曝光单位提供独特的服务，不提供其他地方在纽约大学学院 医学;事实上，吸入接触单位是同类最大的学术设施之一。我们提供 在癌症相关动物研究的实验设计和实施方面的专业知识， 动物实验。我们提供的另一项独特服务是隔离住房和健康监测， 尚未证实无病毒抗体（VAF）状态或携带可移植肿瘤的动物 尚未进行MAP测试;与这些类型的动物一起工作可以进行可行性或试点研究， 用这些动物做的小实验通过提供全面的科学咨询和合作， 在致癌动物模型和致癌物暴露方面，我们的主要目标是促进和加强 科学互动和生产力之间的NYUCI调查。所有人都可以使用这个共享资源 纽约大学癌症研究所的成员和纽约大学社区的其他成员，但癌症研究所 会员优先于非会员。

The objective of the Experimental Animal and Exposure Core Facility is to provide a highly specialized shared resource to support the scientific needs of members of the NYU Cancer Institute for cancer-related animal research in carcinogenesis models and in carcinogen administration. The facility consists of two ntegrated units, the Animal Care and Exposure Unit and the Inhalation Exposure Unit, which provides specialized animal care, technical assistance for experiments with rodent species involving delivery of carcinogenic and toxic chemicals, infectious agents for challenge experiments, or intervention compounds for chemoprevention or chemotherapy via various routes of exposure including inhalation, systemic, dermal, and oral administration. In addition, several radiation equipments for skin irradiation of laboratory animals with electrons, UV and X-ray are also available. The Animal Care and Exposure Unit and the Inhalation Exposure Unit of the resource provide unique services that are not offered elsewhere at NYU School of Medicine; in fact, the Inhalation Exposure Unit is one of the largest academic facilities of its kind. We provide expertise in experimental design and conduct for cancer-related animal studies and necropsy services for animal experiments. Another unique service we provide is segregated housing and health monitoring of animals that do not yet have a proven virus antibody-free (VAF) status or that carry transplantable tumors that have not yet been MAP tested; work with these types of animals allows feasibility or pilot studies and small experiments with these animals. By providing comprehensive scientific consultation and collaboration on carcinogenesis animal models and carcinogen exposure, our primary goal is to facilitate and enhance scientific interaction and productivity among NYUCI investigators. This shared resource is available to all members of the NYU Cancer Institute and other members of the NYU community, but Cancer Institute members have priority over nonmembers.