COBRE FOR SIGNAL TRANSDUCTION AND CANCER PHASE III
COBRE 用于信号转导和癌症 III 期
基本信息
- 批准号:8364913
- 负责人:
- 金额:$ 111万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2011
- 资助国家:美国
- 起止时间:2011-07-15 至 2012-06-30
- 项目状态:已结题
- 来源:
- 关键词:Academic Medical CentersAnimal ModelAppalachian RegionApplications GrantsAreaAwardBasic ScienceBioinformaticsBiometryCancer CenterCancer Center Support GrantCenters of Research ExcellenceCollaborationsCore FacilityEnsureFlow CytometryFundingGoalsGrantGrowthHematopoietic NeoplasmsImageInvestmentsMalignant NeoplasmsMentorsMicroscopeMolecularNCI-Designated Cancer CenterNational Center for Research ResourcesNeoplasm MetastasisPhasePrincipal InvestigatorProcessProteinsResearchResearch InfrastructureResearch PersonnelResourcesShapesSignal TransductionSourceStagingStructureTechnologyTobaccoTrainingTransplantationUnited States National Institutes of HealthUniversitiesWest Virginiacareer developmentcostdesignmalignant breast neoplasmmemberplanetary Atmosphereprogramsranpirnaseresearch and development
项目摘要
This subproject is one of many research subprojects utilizing the resources
provided by a Center grant funded by NIH/NCRR. Primary support for the subproject
and the subproject's principal investigator may have been provided by other sources,
including other NIH sources. The Total Cost listed for the subproject likely
represents the estimated amount of Center infrastructure utilized by the subproject,
not direct funding provided by the NCRR grant to the subproject or subproject staff.
Our long term goal is to establish an NCI designated cancer center for West Virginia (WV) and the surrounding Appalachian region. West Virginia University (WVU) is the flagship university and medical center in the state with no cancer centers in WV currently having NCI designation. Our Phase l-ll CoBREs for Signal Transduction and Cancer (P20) were designed to support basic research development as a critical component of successfully competing for a Cancer Center Support Grant (CCSG) and coincident NCI designation for the WVU Mary Babb Randolph Cancer Center (MBRCC). The specific aims of our Phase I and Phase II CoBREs evolved from an initial focus on junior investigators with a primary goal of nurturing career development and independent funding (Phase I) to a combination of continued support of junior investigators with establishment of a critical mass in targeted thematic areas during Phase II. In addition, the establishment and strengthening of essential core facilities was supported during Phases l-ll and the final stage of this critical core and infrastructure support defines the focus of our Phase III (P30) Transition Award.
Established scientific thematic areas in the MBRCC include Programs focused on the Molecular Mechanisms of EMT and Metastasis, Breast Cancer, Hematopoietic Malignancies and Transplantation, and Translational Tobacco Reduction Research. These Programs provide a structured atmosphere for collaboration and mentoring for the MBRCC members and the platform in which to shape multi-investigator and programmatic grant applications. Relevant to this Transition Award application, projects throughout all of these Programs are supported by the Cores for which support is requested: Flow Cytometry, Microscope Imaging, Animal Models and Imaging, Protein, Biostatistics and Bioinformatics, and Biospecimen Processing. The specific aims of this Phase III Transition Award include (1) support of state-of-the-art technology and expertise in sustainable core facilities that emphasize accessibility and training in which we nurture career development of investigators undertaking cancer related research and (2) enhanced collaboration in the MBRCC, WVU and the state to maximize the impact of CoBRE investment to ensure maximum access to technology required for high quality, extramurally funded research. Emphasis has been placed on strategies to support collaboration, sustainability, and an avoidance of redundant investment to yield the greatest impact of this award on continued growth of the MBRCC, in part, through availability of outstanding core facility support. Collectively, these efforts support our long-term goal of NCI designation.
这个子项目是利用这些资源的众多研究子项目之一
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(1)
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Laura F. Gibson其他文献
Impact of response to thalidomide-, lenalidomide- or bortezomib- containing induction therapy on the outcomes of multiple myeloma patients undergoing autologous transplantation
沙利度胺、来那度胺或硼替佐米诱导治疗的反应对接受自体移植的多发性骨髓瘤患者的结局的影响
- DOI:
- 发表时间:
2012 - 期刊:
- 影响因子:4.8
- 作者:
F. Awan;S. Osman;S. T. Kochuparambil;Laura F. Gibson;S. Remick;Jame Abraham;Michael Craig;Anand Jillella;Mehdi Hamadani - 通讯作者:
Mehdi Hamadani
Prospective Evaluation of A ‘Two-Pronged’ Strategy of Atorvastatin Administration As Acute Graft-Versus-Host Disease (aGVHD) Prophylaxis, to Both Donors and Recipients of Matched Related Donor (MRD) Allogeneic Hematopoietic Cell Transplantation (alloHCT)
- DOI:
10.1016/j.bbmt.2012.11.077 - 发表时间:
2013-02-01 - 期刊:
- 影响因子:
- 作者:
Mehdi Hamadani;Laura F. Gibson;Scot C. Remick;William Petros;Jame Abraham;Soumit Basu;William Tse;Aaron Cumpston;Pam Bunner;Michael Craig - 通讯作者:
Michael Craig
Laura F. Gibson的其他文献
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{{ truncateString('Laura F. Gibson', 18)}}的其他基金
CoBRE for Signal Transduction and Cancer Phase III
CoBRE 用于信号转导和癌症 III 期
- 批准号:
8116200 - 财政年份:2011
- 资助金额:
$ 111万 - 项目类别:
CoBRE for Signal Transduction and Cancer Phase III
CoBRE 用于信号转导和癌症 III 期
- 批准号:
8299627 - 财政年份:2011
- 资助金额:
$ 111万 - 项目类别:
CoBRE for Signal Transduction and Cancer Phase III
CoBRE 用于信号转导和癌症 III 期
- 批准号:
8710277 - 财政年份:2011
- 资助金额:
$ 111万 - 项目类别:
CoBRE for Signal Transduction and Cancer Phase III
CoBRE 用于信号转导和癌症 III 期
- 批准号:
8895998 - 财政年份:2011
- 资助金额:
$ 111万 - 项目类别:
CoBRE for Signal Transduction and Cancer Phase III
CoBRE 用于信号转导和癌症 III 期
- 批准号:
8509721 - 财政年份:2011
- 资助金额:
$ 111万 - 项目类别:
COBRE: WVU: SIGNAL TRANSDUCTION & CANCER: ADMINISTRATIVE CORE
COBRE:西弗吉尼亚大学:信号传导
- 批准号:
8167955 - 财政年份:2010
- 资助金额:
$ 111万 - 项目类别:
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