BioStart: Clinical Research and Education Experiences for Students, Teachers, Par

BioStart：为学生、教师和家长提供临床研究和教育体验

• 批准号: 8040003
• 负责人: HEATHER E KLEINER
• 金额: $ 26.73万
• 依托单位: LOUISIANA STATE UNIV HSC SHREVEPORT
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2015-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8040003
• 关键词: Academy; Animals; Area; Awareness; Basic Science; Biological Sciences; Biomedical Research; Biotechnology; Cancer Center; Clinical Research; Clinical Trials; Communities; Conduct Clinical Trials; Doctor of Philosophy; Education; Educational Activities; Ethical Issues; Event; Faculty; Foundations; Health; Health Sciences; Instruction; Internships; Knowledge; Laboratories; Laboratory Research; Link; Louisiana; Malignant Neoplasms; Medical; Mentors; Parents; Parkinson Disease; Pharmacologic Substance; Phase; Process; Radiation; Recruitment Activity; Research; Research Activity; Research Methodology; Research Project Grants; Safety; Schools; Science; Scientist; Site; Students; Therapeutic; Training; Translational Research; United States National Institutes of Health; Universities; career; drug discovery; expectation; experience; field study; graduate student; high school; interest; lectures; meetings; member; middle school; outreach; posters; programs; public health relevance; symposium; teacher; twelfth grade; web site

DESCRIPTION (provided by applicant): The primary purpose of the BioStart program is to increase the quality and quantity of area graduates in the medical, biotechnology and life sciences fields with the expectation that many of these students will continue on to earn advanced degrees and participate in the regional workforce as medical professionals, research scientists, teachers and technicians. Major partners in this program include Louisiana State University Health Sciences Center at Shreveport (LSUHSC-S), the Biomedical Research Foundation of Northwest Louisiana, and Southwood High School, a public school in Caddo Parish in northwest Louisiana. The program will introduce 25 high school seniors from Southwood's Biotechnology Academy to hands-on, intensive and exciting laboratory research experiences and increase their understanding of the clinical trial process. The participating students and faculty will share these experiences through educational outreach activities that are expected to impact an estimated 250 students, parents, teachers and other segments of the community per year. Specifically, this new, five year Phase I/II SEPA program aims to: 1) Increase knowledge of clinical trials, including medical and life science laboratory practice, research methods, and topics through an internship program whereby high school seniors will conduct a research project under the guidance of a faculty mentor involved in translational and clinical research at LSUHSC-S. Students will attend lectures on specific clinical research topics and careers given by LSUHSC-S faculty and nationally known entrepreneurs and senior management from biotechnology and pharmaceutical companies. Furthermore, students will present their research by participating in at least one poster session and will apply for at least one regional or national science competition. 2) Increase understanding among parents, teachers, students and interested members of the community of the clinical trial process through exposure and interaction with faculty by attending events and symposia given by LSUHSC-S research faculty and graduate students 3) Increase interest in clinical trials, scientific careers and fields of study among middle school students by implementing the following outreach activities: a) presentations by BioStart interns and faculty of their translational and clinical research to groups of middle school students at Sci-Port Louisiana's Science Center - a local hands-on science activity center; b) participating in annual high school fairs at local middle schools to recruit students to the Biotechnology Academy and BioStart programs; and c) creating and distributing collateral materials that describe the BioStart program, and creating a website with program information, student research and activities, and links to the NIH SEPA website. PUBLIC HEALTH RELEVANCE (provided by applicant): The BioStart project is relevant to health through its educational activities to increase the public's understanding of clinical and translational research taking place at LSU Health Sciences Center in Shreveport. By increasing awareness and understanding of clinical trials, there is the expectation that more local residents will participate in these studies. Furthermore, faculty members from LSUHSC-S' Feist-Weiller Cancer Center who participate in the Center for Experimental Cancer Therapeutics (CECAT), will mentor high school students by guiding them in developing research projects relevant to the drug discovery research occurring in their laboratories. Faculty and BioStart student interns will also present their research to the community, including parents, teachers and other students, in a variety of venues.

描述（由申请人提供）：BioStart计划的主要目的是提高医学，生物技术和生命科学领域毕业生的质量和数量，期望这些学生中的许多人将继续获得高级学位，并作为医疗专业人员，研究科学家，教师和技术人员参与区域劳动力。该项目的主要合作伙伴包括位于什里夫波特的路易斯安那州立大学健康科学中心（LSUHSC-S）、路易斯安那西北生物医学研究基金会和路易斯安那西北卡多教区的一所公立学校——南伍德高中。该项目将引入来自索斯伍德生物技术学院的25名高中毕业生，让他们亲身体验密集而令人兴奋的实验室研究，并增加他们对临床试验过程的理解。参与的学生和教师将通过教育推广活动分享这些经验，预计每年将影响约250名学生、家长、教师和社区的其他部分。具体来说，这个新的为期五年的第一/第二阶段环境保护计划旨在：

项目成果

Smooth and Rough Biotypes of Arcanobacterium haemolyticum Can Be Genetically Distinguished at the Arcanolysin Locus.

溶血奥秘杆菌的光滑和粗糙生物型可以在奥秘溶菌素基因座上进行遗传区分。

• DOI: 10.1371/journal.pone.0137346
• 发表时间: 2015
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Ruther,HaleyS;Phillips,Kalyn;Ross,Dolores;Crawford,Alyssa;Weidner,MPayton;Sammra,Osama;Lämmler,Christoph;McGee,DavidJ
• 通讯作者: McGee,DavidJ

Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene.

• DOI: 10.1186/1471-2407-10-540
• 发表时间: 2010-10-08
• 期刊: BMC cancer
• 影响因子: 3.8
• 作者: Becks L;Prince M;Burson H;Christophe C;Broadway M;Itoh K;Yamamoto M;Mathis M;Orchard E;Shi R;McLarty J;Pruitt K;Zhang S;Kleiner-Hancock HE
• 通讯作者: Kleiner-Hancock HE