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The role of the Musashi family in hematopoiesis

The role of the Musashi family in hematopoiesis
武藏家族在造血中的作用
批准号：
8368807
负责人：
Michael Kharas
金额：
$10.26万
依托单位：
SLOAN-KETTERING INST CAN RESEARCH
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-09-28 至 2014-08-31
来源：
https://reporter.nih.gov/project-details/8368807
关键词：
AffectAllelesAplastic AnemiaBindingBiologicalBloodBone Marrow TransplantationBrainBreastCandidate Disease GeneCell CycleCell Fate ControlCell MaintenanceCell physiologyCellsDataDevelopmentDifferentiation TherapyDiseaseDominant-Negative MutationDysmyelopoietic SyndromesEffector CellEquilibriumFailureFamilyFamily memberGene FamilyGenesGeneticGermGoalsHealthHematological DiseaseHematopoiesisHematopoieticHematopoietic NeoplasmsHematopoietic SystemHematopoietic stem cellsHomeostasisInheritedInvestigationKnock-outKnockout MiceMediatingMediationMessenger RNAModelingMolecularMorphologic artifactsMusMyelogenousNeuronsPancytopeniaPathogenesisPathway interactionsPhenotypePlayPost-Transcriptional RegulationPrincipal InvestigatorProcessProteinsRNARNA StabilityRNA-Binding ProteinsRegulationResearchRoleSignal TransductionStem cellsSyndromeSystemTestingTetanus Helper PeptideTetracyclinesTherapeuticTransplantationVertebratesWorkbasebeta cateninbonedesignexhaustiongain of functionin vivoinsightleukemogenesisloss of functionmemberneuron developmentnew therapeutic targetnotch proteinnoveloverexpressionprogenitorprogramspromoterself-renewalsmall hairpin RNAstemstem cell divisiontooltranscription factor

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