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Interleukin-18 and post infarct myocardial remodeling

Interleukin-18 and post infarct myocardial remodeling
Interleukin-18 与梗死后心肌重塑
批准号：
7784475
负责人：
Chandrasekar Bysani
金额：
$0.0万
依托单位：
SOUTHEAST LOUISIANA VETERANS HEALTH CARE
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-04-01 至 2013-12-31
来源：
https://reporter.nih.gov/project-details/7784475
关键词：
70-kDa Ribosomal Protein S6 KinasesActivation AnalysisAcuteAcute myocardial infarctionAddressAngiotensin-Converting Enzyme InhibitorsApoptosisAutoimmune ResponsesBiochemicalCardiacCardiac MyocytesCell Adhesion MoleculesCell DeathCellsCessation of lifeChronicComplexCongestive Heart FailureDataDepositionDeteriorationDevelopmentDilatation - actionDiseaseDown-RegulationExtracellular MatrixFailureFibroblastsFibrosisGenesGoalsGrowth FactorHealthHospitalizationHumanHypertrophyIn VitroIncidenceInfarctionInflammatoryInflammatory ResponseInjuryInterleukin-18Interleukin-6Knock-outKnockout MiceLeft Ventricular HypertrophyLeft Ventricular RemodelingMeasuresMediatingMilitary PersonnelMolecularMorbidity - disease rateMusMyocardialMyocardial InfarctionMyocardiumOutcomePTEN genePathologic ProcessesPathologyPatient CarePatientsPerformancePhasePhenotypePlayPopulationProcessPublishingReactionRegulationReportingRoleSignal TransductionTherapeuticTissuesTransgenic MiceVentricularVentricular RemodelingVeteransabstractingbasechemokinecytokinedesignfetalgain of functionhuman TSC2 proteinimmune activationimprovedin vivoinflammatory markerinjuredinnovationinterleukin-18 receptorloss of functionmigrationmortalitymyocardial infarct sizingnoveloverexpressiontherapeutic target

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