Microsporidiosis: Rational Therapeutics

微孢子虫病：合理治疗

• 批准号: 8321749
• 负责人: Louis M. Weiss
• 金额: $ 41.54万
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2013-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8321749
• 关键词: Acquired Immunodeficiency Syndrome; Address; Amoeba genus; Antiparasitic Agents; Binding; Biological Assay; Biological Availability; Bone Marrow; Categories; Cell Culture Techniques; Cells; Characteristics; Clinical; Computer Simulation; Data; Development; Disease; Dose; Drug Delivery Systems; Drug Design; Encephalitozoon cuniculi; Endothelial Cells; Enterocytozoon bieneusi; Enzyme Inhibition; Enzymes; Eukaryota; Food; Gastrointestinal tract structure; Genes; Grant; Growth; Human; In Vitro; Infection; Invertebrates; Laboratories; Lead; Leishmania donovani; Leishmaniasis; Malaria; Mammals; Methionine; Microsporidia; Microsporidiosis; Modeling; Mus; Nosema corneum; Opportunistic Infections; Organism; Patients; Pharmaceutical Preparations; Plasmodium falciparum; Process; Protozoa; Recombinants; Research; Respiratory Muscles; Saccharomyces cerevisiae; Screening procedure; Structure; Testing; Therapeutic; Therapeutic Agents; Thrombocytopenia; Toxic effect; United States National Institutes of Health; Vertebrates; Water; Yeasts; analog; base; design; fumagillin; gastrointestinal infection; improved; in vitro testing; in vivo; inhibitor/antagonist; killings; methionyl aminopeptidase; nervous system infection; novel; pathogen; reproductive; small molecule libraries; therapeutic target