B 淋巴激酶在 SLE 发展中的作用-猫眼课题宝

B 淋巴激酶在 SLE 发展中的作用

批准号：

8317866

负责人：

Sandra Marie Hayes

金额：

$39.5万

依托单位：

UPSTATE MEDICAL UNIVERSITY

依托单位国家：

美国

项目类别：

财政年份：

2011

资助国家：

美国

项目状态：

已结题

起止时间：

2011-09-01 至 2013-08-31

来源：

https://reporter.nih.gov/project-details/8317866

关键词：

Affect Alleles Antigens Applications Grants Autoantibodies Autoantigens Autoimmune Diseases Autoimmune Process Autoimmunity B-Cell Development B-Lymphocytes BLK gene Binding Biological Assay Biological Models Bone Marrow Candidate Disease Gene Cell Lineage Cells Chimera organism Chronic Defect Development Disease Disease Progression Disease susceptibility Early Diagnosis Etiology Gene Expression Genetic Genetic Transcription Glomerulonephritis Hen Egg Lysozyme Human Immune Immune System and Related Disorders Immune Tolerance Immune system Immunoglobulins Individual Inflammation Lead Location Lupus Lymphocyte Lymphocyte Subset Lymphoid Maintenance Maps Mediating Membrane Modeling Mouse Strains Mus Nature Onset of illness Pathogenesis Pathology Penetrance Phenotype Phosphotransferases Play Predisposition Production Promoter Regions Proteins Receptor Signaling Reporting Risk Risk Factors Role SLEB1 gene Self Tolerance Severities Signal Pathway Susceptibility Gene Systemic Lupus Erythematosus T-Lymphocyte Testing Tissues Transgenes base central tolerance disorder risk genetic variant genome wide association study lupus prone mice mouse model novel peripheral tolerance src-Family Kinases thymocyte

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会议论文

Blk as a Master Regulator of Marginal Zone B Cell Development and Activation

批准号：

8494557
项目类别：
资助金额：

$22.49万
财政年份：

2012
负责人：

Sandra Marie Hayes
依托单位：

UPSTATE MEDICAL UNIVERSITY

Blk as a Master Regulator of Marginal Zone B Cell Development and Activation

批准号：

8386218
项目类别：
资助金额：

$19.94万
财政年份：

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负责人：

Sandra Marie Hayes
依托单位：

UPSTATE MEDICAL UNIVERSITY

Role of Blk in gamma delta T cell development and function

批准号：

7661028
项目类别：
资助金额：

$19.63万
财政年份：

2009
负责人：

Sandra Marie Hayes
依托单位：

UPSTATE MEDICAL UNIVERSITY

Role of Blk in gamma delta T cell development and function

批准号：

7766212
项目类别：
资助金额：

$23.31万
财政年份：

2009
负责人：

Sandra Marie Hayes
依托单位：

UPSTATE MEDICAL UNIVERSITY

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