Role of B Lymphoid Kinase in the Development of SLE

B 淋巴激酶在 SLE 发展中的作用

• 批准号: 8317866
• 负责人: Sandra Marie Hayes
• 金额: $ 39.5万
• 依托单位: UPSTATE MEDICAL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2013-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8317866
• 关键词: Affect; Alleles; Antigens; Applications Grants; Autoantibodies; Autoantigens; Autoimmune Diseases; Autoimmune Process; Autoimmunity; B-Cell Development; B-Lymphocytes; BLK gene; Binding; Biological Assay; Biological Models; Bone Marrow; Candidate Disease Gene; Cell Lineage; Cells; Chimera organism; Chronic; Defect; Development; Disease; Disease Progression; Disease susceptibility; Early Diagnosis; Etiology; Gene Expression; Genetic; Genetic Transcription; Glomerulonephritis; Hen Egg Lysozyme; Human; Immune; Immune System and Related Disorders; Immune Tolerance; Immune system; Immunoglobulins; Individual; Inflammation; Lead; Location; Lupus; Lymphocyte; Lymphocyte Subset; Lymphoid; Maintenance; Maps; Mediating; Membrane; Modeling; Mouse Strains; Mus; Nature; Onset of illness; Pathogenesis; Pathology; Penetrance; Phenotype; Phosphotransferases; Play; Predisposition; Production; Promoter Regions; Proteins; Receptor Signaling; Reporting; Risk; Risk Factors; Role; SLEB1 gene; Self Tolerance; Severities; Signal Pathway; Susceptibility Gene; Systemic Lupus Erythematosus; T-Lymphocyte; Testing; Tissues; Transgenes; base; central tolerance; disorder risk; genetic variant; genome wide association study; lupus prone mice; mouse model; novel; peripheral tolerance; src-Family Kinases; thymocyte