Regulation and functions of mast cell-derived IL-33

肥大细胞来源的 IL-33 的调节和功能

• 批准号: 8308810
• 负责人: PAUL J BRYCE
• 金额: $ 38.13万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-15 至 2013-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8308810
• 关键词: Address; Adipocytes; Anaphylaxis; Antigens; Asthma; Atherosclerosis; Autoimmunity; Basophils; Binding; Binding Sites; Brain; Calcineurin; Calcium; Cell Nucleus; Cells; Chromatin; Data; Dendritic Cells; Disease; Edetic Acid; Endothelial Cells; Epithelial Cells; Esthesia; Family; Family member; Fibroblasts; Fibrosis; Food Hypersensitivity; Gene Expression; Generations; Genes; Genetic Transcription; Goals; Hypersensitivity; IgE; Immune response; Immunity; Immunomodulators; In Vitro; Indium; Infection; Inflammation; Inflammation Mediators; Inflammatory; Inflammatory Bowel Diseases; Inflammatory Response; Interleukin-1; Interleukin-18; Interleukins; Ionomycin; Lead; Lung; Lymphocyte; Malignant Neoplasms; Mediating; Mediator of activation protein; Messenger RNA; Modeling; Molecular Profiling; Mus; Nuclear; Orphan; PTPN1 gene; Pain; Parasites; Pathway interactions; Pattern; Production; Promoter Regions; Proteins; Recombinant Interleukins; Regulation; Rest; Role; Site; Skin; Source; Stomach; Testing; Tissues; Up-Regulation; autocrine; base; chromatin remodeling; crosslink; cytokine; eosinophil; in vivo; mRNA Expression; macrophage; mast cell; member; nuclear factors of activated T-cells; overexpression; promoter; receptor; reconstitution; response

项目成果

Inducible IL-33 expression by mast cells is regulated by a calcium-dependent pathway.

• DOI: 10.4049/jimmunol.1201224
• 发表时间: 2012-10-01
• 期刊: Journal of immunology (Baltimore, Md. : 1950)
• 作者: Hsu CL;Bryce PJ
• 通讯作者: Bryce PJ