Listeria-based vaccines engineered to modulate the innate immune system
Listeria-based vaccines engineered to modulate the innate immune system
批准号:
8296801
负责人:
DANIEL A PORTNOY
金额:
$35.51万
依托单位国家:
美国
项目类别:
财政年份:
2011
资助国家:
美国
项目状态:
已结题
起止时间:
2011-08-01 至 2013-07-31
关键词:
AffectAmino AcidsAntibody FormationAntigensAttenuatedBacteriophagesBiological AssayBreedingCD8B1 geneCancer VaccinesCaspase-1Cell DeathCellsCellular ImmunityCellular biologyChimeric ProteinsChromosomesClinicalClinical TrialsCollaborationsCollectionCommunicable DiseasesCytolysisCytosolDNADendritic CellsDevelopmentDoseDrug FormulationsEngineeringFlagellinGenerationsGenesGeneticGoalsGrowthHumanImmuneImmune responseImmune systemImmunityImmunizationIn VitroInfectionInterferon Type IInterferonsInterleukin-1Knockout MiceKnowledgeLaboratoriesLeadLifeLife Cycle StagesLigandsListeriaListeria monocytogenesMalariaMalignant NeoplasmsMeasuresMediatingModelingMonitorMusMutationNatural ImmunityOvalbuminPathway interactionsPlasmodium bergheiPre-Clinical ModelProductionPropertyProteinsRecombinantsRoleT cell responseT-LymphocyteT-Lymphocyte EpitopesTestingTherapeuticTimeVaccinesVacciniaVacciniumWorkabstractingacquired immunitybasebiodefensecell mediated immune responsecytotoxicityefflux pumpfitnessglobal healthimmunogenicityin vivoinsightmacrophagemouse modelmutantnonhuman primateoverexpressionpathogenphosphoric diester hydrolasepreclinical studyresponsetherapeutic vaccinetoolvaccine candidatevaccine developmentvectorvector vaccinevector-based vaccine
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会议论文
The role of Listeria cyclic-di-AMP during infection and immunity
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批准号:8234225
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项目类别:
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资助金额:$43.31万
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财政年份:2011
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负责人:DANIEL A PORTNOY
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依托单位:
Administrative Core A
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批准号:8234235
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项目类别:
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资助金额:$18.0万
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财政年份:2011
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负责人:DANIEL A PORTNOY
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依托单位:
Project 1: Listeria metabolites and innate immunity
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批准号:10190578
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项目类别:
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资助金额:$49.85万
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财政年份:2004
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负责人:DANIEL A PORTNOY
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依托单位:
Intracellular Pathogens and Innate Immunity
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批准号:7177234
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项目类别:
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资助金额:$5.76万
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财政年份:2004
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负责人:DANIEL A PORTNOY
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依托单位:
Administrative Core A
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批准号:9977102
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项目类别:
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资助金额:$16.55万
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财政年份:2004
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负责人:DANIEL A PORTNOY
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依托单位:
The intersection of innate and adaptive immunity to intracellular pathogens
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批准号:10655288
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项目类别:
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资助金额:$232.54万
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财政年份:2004
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负责人:DANIEL A PORTNOY
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依托单位:
Administrative Core A
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批准号:10190576
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项目类别:
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资助金额:$17.48万
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财政年份:2004
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负责人:DANIEL A PORTNOY
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依托单位:
Intracellular pathogens and innate immunity
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批准号:8507131
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项目类别:
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资助金额:$176.59万
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财政年份:2004
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负责人:DANIEL A PORTNOY
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依托单位:
Project 1: Innate immune responses triggered by Listeria monocytogenes
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批准号:9977105
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项目类别:
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资助金额:$53.08万
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财政年份:2004
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负责人:DANIEL A PORTNOY
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依托单位:
The intersection of innate and adaptive immunity to intracellular pathogens
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批准号:10400179
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项目类别:
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资助金额:$233.32万
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财政年份:2004
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负责人:DANIEL A PORTNOY
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依托单位:
Project 1: Listeria metabolites and innate immunity
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批准号:10400182
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项目类别:
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资助金额:$55.83万
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财政年份:2004
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负责人:DANIEL A PORTNOY
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依托单位:
Intracellular Pathogens and Innate Immunity
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批准号:7027678
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项目类别:
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资助金额:$200.87万
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财政年份:2004
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负责人:DANIEL A PORTNOY
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依托单位:
Intracellular Pathogens and Innate Immunity
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批准号:7188971
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项目类别:
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资助金额:$204.97万
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财政年份:2004
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负责人:DANIEL A PORTNOY
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依托单位:
Manipulation of Host Innate Immunity by Listeria
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批准号:6880450
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项目类别:
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资助金额:$11.64万
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财政年份:2004
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负责人:DANIEL A PORTNOY
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依托单位:
Intracellular pathogens and innate immunity
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批准号:7860371
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项目类别:
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资助金额:$251.71万
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财政年份:2004
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负责人:DANIEL A PORTNOY
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依托单位:
Intracellular Pathogens and Innate Immunity
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批准号:6861549
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项目类别:
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资助金额:$70.05万
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财政年份:2004
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负责人:DANIEL A PORTNOY
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依托单位:
Administrative Core A
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批准号:10400180
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项目类别:
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资助金额:$17.14万
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财政年份:2004
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负责人:DANIEL A PORTNOY
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依托单位:
Intracellular pathogens and innate immunity
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批准号:8301525
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项目类别:
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资助金额:$190.74万
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财政年份:2004
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负责人:DANIEL A PORTNOY
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依托单位:
Intracellular pathogens and innate immunity
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批准号:9288105
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项目类别:
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资助金额:$211.7万
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财政年份:2004
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负责人:DANIEL A PORTNOY
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依托单位:
Intracellular pathogens and innate immunity
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批准号:9977087
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项目类别:
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资助金额:$208.29万
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财政年份:2004
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负责人:DANIEL A PORTNOY
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依托单位:
海外基金