The role of indoleamine 2-3 dioxygenase in marginal zone-mediated tolerance

吲哚胺2-3双加氧酶在边缘区介导的耐受中的作用

• 批准号: 8301218
• 负责人: Tracy L McGaha
• 金额: $ 33.54万
• 依托单位: AUGUSTA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-01 至 2013-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8301218
• 关键词: Address; Aftercare; Animals; Antigens; Apoptotic; Autoantigens; Autoimmune Diseases; Autoimmune Process; Autoimmunity; Behavior; Biology; Blood Circulation; Bone Marrow; Cell Fate Control; Cells; Chronic; Data; Development; Dioxygenases; Disease; Disease Progression; Enzymes; Essential Amino Acids; Exposure to; Goals; IgG Receptors; Immune Tolerance; Immune response; Inflammation; Inflammatory; Inflammatory Response; Injection of therapeutic agent; Interferons; Interleukin-6; Lead; Ligation; Literature; Lupus; Mediating; Metabolic Clearance Rate; Mus; Particulate Matter; Play; Predisposition; Prevention; Process; Regulatory Pathway; Risk; Role; Source; Spleen; Syndrome; Systemic Lupus Erythematosus; T cell response; TNF gene; Testing; Therapeutic; Therapeutic Intervention; Toll-like receptors; Tryptophan; base; cytokine; in vivo; indolamine; indoleamine; insight; lupus prone mice; lupus-like; macrophage; mouse model; new therapeutic target; novel; prevent; response; systemic autoimmune disease

项目成果

O death where is thy sting? Immunologic tolerance to apoptotic self.

• DOI: 10.1007/s00018-013-1261-0
• 发表时间: 2013-10
• 期刊: CELLULAR AND MOLECULAR LIFE SCIENCES
• 影响因子: 8
• 作者: Ravishankar, Buvana;McGaha, Tracy L.
• 通讯作者: McGaha, Tracy L.