Regulation of cell division in Trypanosoma brucei

布氏锥虫细胞分裂的调节

• 批准号: 8297326
• 负责人: Ziyin Li
• 金额: $ 37.92万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-25 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8297326
• 关键词: Actins; Actomyosin; Address; African; African Trypanosomiasis; Animals; Anterior; Antigenic Variation; Biochemical; Biological; Cell Cycle; Cell Cycle Proteins; Cell Cycle Regulation; Cell Nucleus; Cell division; Cells; Centrosome; Chromosome Segregation; Chromosomes; Complex; Country; Cytokinesis; Disease; Drug Delivery Systems; Flagella; Genetic; Genetic Screening; Goals; Guanosine Triphosphate Phosphohydrolases; Human; Immune system; Infection; Kinesin; Kinetochores; Laboratories; Link; MCM2 gene; Mediating; Microtubule-Organizing Center; Microtubules; Mitosis; Mitotic; Mitotic spindle; Molecular; Myosin ATPase; Outcome Study; Parasites; Parasitic Diseases; Pathway interactions; Pharmaceutical Preparations; Phosphorylation; Play; Process; Protein Kinase; Proteins; RNA Interference; Regulation; Replication Initiation; Risk; Role; Spatial Distribution; System; Testing; Trypanosoma; Trypanosoma brucei brucei; Trypanosomiasis; World Health Organization; aurora B kinase; base; chemotherapy; constriction; drug development; genetic regulatory protein; human PLK1 protein; migration; novel; public health relevance; spindle pole body; vector

项目成果

A kinetoplastid-specific kinesin is required for cytokinesis and for maintenance of cell morphology in Trypanosoma brucei.

细胞因子和维持锥虫锥虫的细胞形态所必需的动力质体特异性驱动蛋白。

• DOI: 10.1111/j.1365-2958.2011.07951.x
• 发表时间: 2012-02
• 期刊: Molecular microbiology
• 影响因子: 3.6
• 作者: Hu L;Hu H;Li Z
• 通讯作者: Li Z

Structure-function relationship of the Polo-like kinase in Trypanosoma brucei.

布氏锥虫 Polo 样激酶的结构-功能关系。

• DOI: 10.1242/jcs.094243
• 发表时间: 2012
• 期刊: Journal of cell science
• 影响因子: 4
• 作者: Yu,Zhonglian;Liu,Yi;Li,Ziyin
• 通讯作者: Li,Ziyin