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Host defense against poxviruses and viral immune evasion

Host defense against poxviruses and viral immune evasion
宿主对抗痘病毒和病毒免疫逃避的防御
批准号：
8295047
负责人：
Liang Deng
金额：
$45.04万
依托单位：
SLOAN-KETTERING INST CAN RESEARCH
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
项目状态：
已结题
起止时间：
2011-07-15 至 2013-06-30
来源：
https://reporter.nih.gov/project-details/8295047
关键词：
3-methyladenineAddressAntiviral AgentsAttenuatedAutophagocytosisAutophagosomeAwardBindingBinding ProteinsBiochemicalCase Fatality RatesChloroquineCommunicable DiseasesCytosolDNADNA VirusesDefense MechanismsDendritic CellsDevelopmentDiseaseDouble-Stranded RNAEczema VaccinatumElectron Transport Complex IIIEpithelial CellsGenerationsGeneticGoalsHIVHost DefenseHumanIRF3 geneImmuneImmune responseImmune systemImmunizationImmunotherapyInfectionInfectious AgentInterferonsKnowledgeMalariaMalignant NeoplasmsMediatingModelingModified Vaccinia Virus AnkaraMolecularMolecular ProbesMonkeypoxMusMyxomaMyxoma virusNational Institute of Allergy and Infectious DiseaseNatural ImmunityNutrientOncolyticOrthopoxvirusOryctolagus cuniculusPathogenesisPathway interactionsPattern recognition receptorPlayPopulationPoxviridaePoxviridae InfectionsPreventive InterventionProductionProteinsRNA Polymerase IIIRecording of previous eventsResearchResearch PersonnelRoleSignal PathwaySkinSmallpoxSmallpox VaccineStarvationStressTechnologyTestingTherapeutic InterventionTimeToll-like receptorsTuberculosisVaccine DesignVaccinesVacciniaVaccinia virusVacciniumViralViral PathogenesisViral ProteinsVirionVirulenceVirulence FactorsVirusVirus InhibitorsZ-Form DNAadaptive immunitybafilomycin A1basedesigneIF-2 Kinaseimprovedin vivoinhibition of autophagyinhibitor/antagonistinsightinterestmacrophagenoveloncolytic vectorpathogenresponsesensortherapeutic vaccinevaccination strategyvector vaccinevirus host interactionweapons

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