Supercomputer Linux Cluster for Genomics and Proteomics

用于基因组学和蛋白质组学的超级计算机 Linux 集群

• 批准号: 8051874
• 负责人: David Albert Schwartz
• 金额: $ 59.69万
• 依托单位: NATIONAL JEWISH HEALTH
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-15 至 2013-02-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8051874
• 关键词: Data; Funding; Future Generations; Genetic; Genetic Polymorphism; Genomics; Health; High Performance Computing; Immune System Diseases; Institution; Linux; Lung diseases; Medicine; Molecular Genetics; Performance; Proteins; Proteomics; Research Personnel; Resources; Supercomputing; System; United States National Institutes of Health; base; computing resources; cost effective; follower of religion Jewish; genetic analysis; human disease; meetings; patient population; success; supercomputer

DESCRIPTION (provided by applicant): National Jewish Health (NJH) is requesting funding for a Dell High Performance Linux supercomputing resource. The addition of a high-performance computing resource at NJH will allow the currently-funded NIH- sponsored studies in genetics, genomics, and proteomics the greatest opportunity for success in elucidating the genetic and molecular basis of pulmonary and immunologic disease in our patient populations. The computational power required for the imputation and analysis of genetic data and predictions for the protein conformational impact of polymorphism is enormous. We have proposed a modest cost-effective Linux-based cluster system that will meet the current and foreseeable computational needs of our NIH-funded investigators and will allow the future generation of researchers at our institution to explore the genetic basis of human disease and personalized medicine.

描述（由申请人提供）：National Jewish Health （NJH）正在为戴尔高性能Linux超级计算资源申请资金。NJH的高性能计算资源的增加将使目前由NIH资助的遗传学、基因组学和蛋白质组学研究有最大的机会成功地阐明我们患者群体中肺部和免疫疾病的遗传和分子基础。对遗传数据的输入和分析以及对多态性对蛋白质构象影响的预测所需要的计算能力是巨大的。我们已经提出了一个适度的、具有成本效益的基于linux的集群系统，它将满足我们nih资助的研究人员当前和可预见的计算需求，并将允许我们机构的下一代研究人员探索人类疾病和个性化医疗的遗传基础。