Cardiovascular Sensory Transduction by Acid Sensing Ion Channels

酸敏感离子通道的心血管感觉转导

• 批准号: 8154140
• 负责人: FRANCOIS M ABBOUD
• 金额: $ 60.02万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-15 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8154140
• 关键词: ASIC channel; Accounting; Acidosis; Amino Acid Sequence; Atherosclerosis; Baroreflex; Binding; Blood Circulation; Blood Pressure; Cardiovascular system; Carotid Body; Cells; Chemicals; Chemoreceptors; Co-Immunoprecipitations; Complex; Conscious; Data; Dependence; Dysautonomias; Electrophysiology (science); Equilibrium; Experimental Models; Gene Transfer; Glomus Cell; Heart Rate; Heart failure; Hypercapnia; Hyperoxia; Hypertension; Hypoxia; Immunohistochemistry; Impairment; Inbred SHR Rats; Infusion procedures; Kidney; Knock-out; Laboratories; Measurement; Mechanics; Mediating; Membrane; Membrane Potentials; Messenger RNA; Modeling; Molecular; Mus; Nerve; Neurons; Nitroprusside; Nodose Ganglion; Pathologic; Phenylephrine; Physiological; Potassium Channel; Pressoreceptors; Property; Prostaglandins I; Protons; Rattus; Receptor Signaling; Reflex action; Reporting; Residual state; Rodent; Role; Sensory; Signal Transduction; Site; Small Interfering RNA; Structure of phrenic nerve; Testing; Toxin; Transfection; awake; base; carotid sinus; electrical property; extracellular; heart rate variability; large-conductance calcium-activated potassium channels; mRNA Expression; neurogenic hypertension; overexpression; pressure; response; sensor