ACTIVATED T ANTIGEN IN ASSOCIATION WITH NECROTIZING ENTERCOLITIS AND/OR SEPSIS

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 我们建议确定的频率活化T抗原在坏死性小肠结肠炎（NEC），败血症，和/或菌血症的婴儿相比，对照组的婴儿没有这些条件。婴儿将通过特定标准确定为符合上述条件之一，并在72小时内进行血液活性T和游离血浆血红蛋白检测。我们不仅能够确定该组中活化T的频率，而且还可以确定活化T的婴儿在溶血方面是否有显著差异。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. We propose to determine the frequency of activated T antigen in infants with necrotizing enterocolitis (NEC), sepsis, and or bacteremia compared to a control group of infants without these conditions. Infants will be identified by specific criteria as meeting one of the above conditions and within 72 hours have blood tested for activated T as well as free plasma hemoglobin. We will not only be able to determine the frequency of activated T in this group, but also determine if there is a significant difference in hemolysis in those infants with activated T.