CENTER FOR AIDS RESEARCH (CFAR)

艾滋病研究中心 (CFAR)

• 批准号: 8357388
• 负责人: JAMES W. CURRAN
• 金额: $ 17.84万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357388
• 关键词: AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Basic Science; Behavioral Research; Biological Assay; Clinical Research; Clinical Virology; Consultations; Data Analyses; Device or Instrument Development; Epidemiologist; Equipment; Faculty; Flow Cytometry; Funding; Gene Expression; Grant; HIV; Human; Immunology; Incidence; Laboratories; National Center for Research Resources; Prevalence; Primary Prevention; Primates; Principal Investigator; Research; Research Infrastructure; Research Personnel; Research Support; Resources; Reverse Transcriptase Polymerase Chain Reaction; Sampling; Savings; Secondary Prevention; Services; Source; Staining method; Stains; Study Subject; Time; Training; Translational Research; United States National Institutes of Health; Vaccines; assay development; base; cost; cytokine; graduate student; member; men who have sex with men; nonhuman primate

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Center for AIDS Research (CFAR) at Emory facilitates scientifically rigorous basic, clinical, translational, and behavioral research in HIV/AIDS and connects HIV/AIDS researchers within and across scientific fields with the objective of increasing NIHfunded research in the primary and secondary prevention of HIV and its aftermath. The Immunology Core, at the Emory Vaccine Center at Yerkes, produced a multicolor cytokine flow cytometry staining panel for human and non-human primate samples. The panel provides substantial resource savings for investigators, as it is quicker and requires fewer samples and materials. CFAR and EVC members, including Drs. Ahmed, Amara, Hunter, Villinger, and outside laboratories and users of the Yerkes National Primate Research Center have successfully used the panel. The CFAR Pre-Clinical Virology Core at Yerkes, provides instrument and assay development training and consultation to fellows and graduate students to facilitate and accelerate the pace of research in investigator's labs. For example, the Core provided full-service, real-time RT-PCR-based gene expression assays and data analysis assistance to Colleen Kelley (ID Fellow) who collaborated with Patrick Sullivan (epidemiologist) to expand his study "Explaining the difference in HIV prevalence and incidence between white and black men who have sex with men" (R01 MH085600). The Core's support enlarged the pool of available study subjects and brought new investigators into HIV/AIDS research. Through the strategic use of funds, the CFAR assisted in the recruitment of leading senior and junior faculty and provided essential equipment to a number of CFAR and EVC-affiliated investigators.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 Emory的艾滋病研究中心（CFAR）促进了艾滋病毒/艾滋病的科学严格，临床，转化和行为研究，并将科学领域内和跨科学领域的艾滋病毒/艾滋病研究人员联系起来，目的是增加NIH资助的HIV和次级预防艾滋病毒及其后的研究。 在Yerkes的Emory疫苗中心的免疫学核心生产了人类和非人类灵长类动物样品的多色细胞因子流式细胞仪染色面板。 该面板为调查人员提供了可观的资源节省，因为它更快，需要更少的样品和材料。 CFAR和EVC成员，包括Drs。艾哈迈德（Ahmed），阿玛拉（Amara），亨特（Hunter），维林格（Villinger）和外部实验室以及耶克斯国家灵长类动物研究中心（Yerkes National Pread）研究中心的使用者成功使用了该小组。 Yerkes的CFAR前病毒学核心，向研究员和研究生提供工具和测定开发培训和咨询，以促进和加速研究人员实验室的研究步伐。例如，核心为Colleen Kelley（ID研究员）提供了全方位服务的，实时的基于RT-PCR的基因表达分析和数据分析帮助，他们与Patrick Sullivan（Epidemiogist）合作，以扩大他的研究“解释HIV患病的差异和与男性发生性关系的白人和黑人男性之间的差异”（R01 MH0855600）。 核心的支持扩大了可用的研究主题，并将新的研究人员带入了艾滋病毒/艾滋病研究。 通过战略利用资金，CFAR协助招募了领先的高级和初级教师，并为许多CFAR和EVC相关的研究人员提供了必不可少的设备。