权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

A Low Power Wireless Pulse Oximeter Sensor for Unobtrusive Wearable Applications

适用于低调可穿戴应用的低功耗无线脉搏血氧计传感器

基本信息

批准号：
8121995
负责人：
Patrick Lichter
金额：
$ 15.74万
依托单位：
KORONIS BIOMEDICAL TECHNOLOGIES CORPORAT
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
起止时间：
2011-08-15 至 2013-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8121995
关键词：
Address Agreement Biomedical Technology Blood gas Breathing Cessation of life Characteristics Chronic Chronic Obstructive Airway Disease Clinical Clinics and Hospitals Computer software Cost of Illness Country Custom Data Development Devices Emergency Situation Employee Strikes Fingers Health Hearing Aids Heart Rate Hemoglobin Home environment Hospitalization Hour Hypoxemia Industry Lasers Light Lung Lung diseases Marketing Measurement Medical Medical Device Medicare Monitor Outpatients Oxygen Oxygen Therapy Care Patients Performance Persons Phase Physiologic Monitoring Physiologic pulse Principal Investigator Protocols documentation Pulse Oximetry Rehabilitation therapy Respiratory Failure Role Sleep Solutions Source Supplementation Surface Technology Testing Therapeutic Time United States Weight Wireless Technology base design experience improved instrumentation programs prototype sensor

项目摘要

DESCRIPTION (provided by applicant): Koronis Biomedical Technology Corporation (KBT) proposes to develop and evaluate a miniature ultralow power pulse oximeter for long-term wearable monitoring. There continues to be a clinical need for an unobtrusive pulse oximeter sensor that is small and can be worn comfortably for extended periods of time without battery change or recharge. This program will direct development efforts towards a home based monitor for chronic obstructive pulmonary disease (COPD) patients on long-term oxygen therapy (LTOT). The benefits of long-term oxygen supplementation in COPD patients with hypoxemia are well established. Currently, the standard approach to prescribing oxygen uses a static assessment of oxygen requirements in a hospital or clinic setting. The assumption behind this approach is that patients will maintain"therapeutic" hemoglobin oxygen saturation (SpO2) in the outpatient setting. Recent studies with 24 hour pulse oximetry monitoring have demonstrated that the standard prescription does not properly oxygenate most patients. Several technical challenges must be overcome to address a sensor for long-term continuous pulse oximetry monitoring. In order to design more compact sensors and improved wearable instrumentation, perhaps the most critical challenges are to develop more power efficient and low weight devices. Additionally, before wearable devices can be used effectively in the home, they must become unobtrusive and should not hinder a person's mobility. Standard finger pulse oximeters are not practical for many applications because they can interfere with normal daily tasks. PUBLIC HEALTH RELEVANCE: Chronic obstructive pulmonary disease (COPD) causes more than 500,000 hospitalizations and more than 100,000 deaths in the United States each year. There is a general agreement that patients with COPD who are developing chronic respiratory failure benefit from long-term oxygen therapy (LTOT).

描述（由申请人提供）：Koronis Biomedical Technology Corporation（KBT）拟开发和评估一种用于长期可穿戴监测的微型超低功率脉搏血氧仪。临床上仍然需要一种不显眼的脉搏血氧计传感器，该脉搏血氧计传感器体积小，并且可以在不更换电池或充电的情况下舒适地佩戴较长时间。该计划将指导开发工作，为长期氧疗（LTOT）的慢性阻塞性肺疾病（COPD）患者提供基于家庭的监测器。COPD低氧血症患者长期吸氧的益处已得到充分证实。目前，开氧气处方的标准方法是在医院或诊所环境中对氧气需求进行静态评估。这种方法背后的假设是，患者将在门诊环境中维持“治疗性”血红蛋白氧饱和度（SpO2）。最近的24小时脉搏血氧监测研究表明，标准处方不能适当地使大多数患者恢复健康。必须克服若干技术挑战以解决用于长期连续脉搏血氧饱和度监测的传感器。为了设计更紧凑的传感器和改进的可穿戴仪器，也许最关键的挑战是开发更节能和更轻的设备。此外，在可穿戴设备可以在家中有效使用之前，它们必须变得不显眼，并且不应该妨碍人的移动性。标准的手指脉搏血氧仪对于许多应用来说是不实用的，因为它们会干扰正常的日常任务。公共卫生相关性：在美国，慢性阻塞性肺病（COPD）每年导致超过50万人住院治疗和超过10万人死亡。人们普遍认为，发生慢性呼吸衰竭的COPD患者可从长期氧疗（LTOT）中获益。