NEURODEGENERNATION RESEARCH PROGRAM (NRP)

该子项目是利用资源的许多研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 子项目的主要研究者可能是由其他来源提供的， 包括其它NIH来源。 为子项目列出的总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 摘要 RCMI NPR的主要目标是建立神经变性研究计划（NRP），以加强佛罗里达A & M大学在这一研究领域的基础设施，并提高其教师的研究生产力。建立神经退行性疾病研究计划的潜在影响不能被夸大。 神经退行性疾病对一般公众，特别是老年人的健康有重大影响。此外，该计划将对增加全国少数民族神经科学家的数量产生重大影响。 FAMU药学和药物科学学院是全国领先的机构，在培养非洲裔美国人在制药科学和神经科学领域的博士学位。因此，本申请的目的是通过增加现有的人力基础设施和研究资源来开发神经退行性疾病研究。长期目标是建立一个专注于神经退行性疾病的创新和多学科计划。 具体目标是：1）支持一个初级FAMU研究员的神经变性研究试点项目。该项目预计将产生将被公布的数据，帮助建立研究者，并允许教师有机会寻求和获得独立的研究资金; 2）支持研究设施的发展，以增加神经退行性疾病研究的创新。研究设施将包括：a）分子神经生物学，B）细胞成像，和c）神经化学/受体结合; 3）提供内部支持以启动神经变性研究项目;和4）提高神经变性研究人员的研究能力，这将使他们能够通过建立内部和外部指导计划来竞争主流资金，并以小型休假的形式提供培训和学术互动，研讨会和讲习班。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. ABSTRACT The major goals of the RCMI NPR are to establish Neurodegeneration Research Program (NRP), to enhance the infrastructure in this area of research at Florida A&M University and to increase research productivity of its faculty. The potential impact of establishing a Neurodegeneration research program cannot be overstated. Neurodegenerative diseases have a major impact on the health of the general public in and the elderly population in particular. Moreover, this program will have a major impact toward increasing the number of minority neuroscientists in the Nation. FAMU College of Pharmacy and Pharmaceutical Sciences is the leading institution, nationwide, in training African Americans with PhD's in pharmaceutical sciences and in the area of neuroscience. Therefore, the purpose of this application is to develop Neurodegeneration research by adding onto the human infrastructure and research resources that already exist. The long-term objectives are to establish an innovative and multidisciplinary program focusing on Neurodegeneration. The specific aims are to: 1) support a Neurodegeneration research pilot project of a junior FAMU investigator. The project is expected to generate data that will be published, help establish the investigator and allow opportunities for faculty to seek and obtain independent research funds; 2) support the development of research facilities to increase innovation of Neurodegeneration diseases research. Research facilities will include: a) Molecular Neurobiology, b) Cellular Imaging, and c) Neurochemistry/Receptors binding; 3) offer in-house support to start Neurodegeneration research projects; and 4) enhance the research capabilities of Neurodegeneration investigators that will put them in a position to compete for mainstream funding through the establishment of internal and external mentoring program and provide training and academic interaction in the form of mini-sabbatical, seminars and workshops.