Adolescents' Disease Empowerment and Persistency Technology for Asthma

描述（由申请人提供）：申请人是一名过敏症专科医生/免疫学家，寻求成为一名独立的行为干预调查员，以促进患有持续性哮喘的城市非裔美国青少年的健康。建议的干预措施侧重于同伴支持，应对同伴小组问题解决会议，记录有关服用哮喘控制药物的障碍和克服这些障碍的方法的信息，以及研究参与者在一周内通过MPS播放器（称为Media Hub）的音乐歌曲将这些信息传递给彼此。这些信息通过青少年疾病授权和持久性技术（ADEPT）哮喘网络控制系统传递到媒体中心。职业发展计划提供进一步的教育、培训和指导，以进行文化敏感的、基于技术的干预措施的行为控制试验，以促进持续的变化。该研究计划得益于先前的试点工作，提出了一个增加依从性的概念模型，然后对该模型中的每个步骤进行了测试。这个奖项的主要导师。Lynda H. Powell博士是行为试验方法方面的专家，她将确保申请人应用适当的理论和方法来测试她的概念模型。共同导师和顾问将在定性研究、行为改变的行为和社会原则以及依从性的具体领域提供额外的指导。该研究计划旨在：确定提高ADEPT和其他新提出的基于技术平台的能力的方法，以增加依从性；对新改进的干预措施进行“概念验证”试点研究；并进行一项行为对照试验，测试ADEPT提高依从性的有效性。在本奖项结束时，申请人将以独特的方式提交一份ROl资助申请，以开展一项大规模的行为随机试验，评估ADEPT干预措施在改善城市非裔美国哮喘青少年重要健康结果方面的有效性。相关性（见说明）：市中心非裔美国青少年因哮喘而急诊室就诊和住院的比率惊人，需要紧急干预。本研究的最终目标是通过使用同伴支持来降低这一人群中哮喘的发病率和死亡率，并通过文化敏感、基于技术的MP3播放器平台来增强对日常控制药物的依从性。（摘要结束）

DESCRIPTION (provided by applicant): The applicant is an Allergist/lmmunologist who seeks to develop a career as an independent investigator of behavioral interventions that promote the health of urban African American adolescents with persistent asthma. The proposed intervention focuses on peer support, coping peer group problem-solving sessions to record messages about barriers to taking controller medications for asthma and ways to overcome these barriers, and the delivery of these messages developed by study participants themselves to each other throughout the week between music tracks on an MPS player known as the Media Hub. The messages are delivered via the Adolescents' Disease Empowerment and Persistency Technology (ADEPT) for asthma Network Control System to the Media Hub. The career development plan provides further education, training, and mentorship needed to conduct behavioral controlled trials of culturally sensitive, technologybased interventions to promote sustained change. The research plan benefits from prior pilot work, proposes a conceptual model for increasing adherence, and then tests each step in this model. The primary mentor for this award. Dr. Lynda H. Powell, is an expert in behavioral trial methodology and will ensure the applicant applies appropriate theory and methodology to test her conceptual model. The Co-Mentor and Advisors will provide additional guidance in the specific areas of qualitative research, behavioral and social principles of behavior change, and adherence. The research plan aims to: identify ways to improve the ability of ADEPT and other newly proposed technology based platforms to increase adherence; conduct a "proof of concept" pilot study of the newly refined intervention; and conduct a behavioral controlled trial testing the efficacy of ADEPT to improve adherence. At the end of this award, the applicant will be uniquely positioned to submit an ROl grant application to conduct a large-scale behavioral randomized trial evaluating the effectiveness of the ADEPT intervention to improve important health outcomes in urban African American adolescents with asthma. RELEVANCE (See instructions): Alarming rates of emergency room visits and hospitalizations for asthma in inner-city African American adolescents require urgent intervention. The ultimate goal of this research is to reduce the morbidity and mortality of asthma in this population through the use of peer support, enhanced by a culturally sensitive, technology-based MP3 player platform aimed at increasing adherence to daily controller medications. (End of Abstract)