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Measuring Living Kidney Transplantation at Renal Transplant Centers

测量肾移植中心的活体肾移植情况

基本信息

批准号：
8110570
负责人：
PETER PHILIP REESE
金额：
$ 13.17万
依托单位：
UNIVERSITY OF PENNSYLVANIA
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-07-01 至 2012-12-30
项目状态：
已结题

项目摘要

DESCRIPTION (provided by applicant): Dr. Peter P. Reese, a National Research Service Award Fellow in the Renal Division at the University of Pennsylvania School of Medicine, is applying for a K-23 Patient Oriented Research Career Development Award to acquire further experience and skills for an academic career as an independent investigator focused on transplantation. This proposal outlines a 5-year multi-disciplinary training program consisting of research, coursework, and mentoring by Dr. Harold I. Feldman, Director of the Clinical Epidemology Unit at Penn's Center for Clinical Epidemology and Biostatistics. Dr. Reese will pursue coursework in epidemiology, biostatistics, health policy and medical ethics which pertain directly to his proposed K-23 project, and which will prepare him to lead future independent research programs related to renal transplantation. The prevalence of end-stage renal disease (ESRD) in the United States (US) continues to climb, with devastating consequences for patients including an elevated risk of cardiovascular death and the burden of chronic dialysis. The growing ESRD population has intensified the demand for kidney transplantation, which has been shown to reduce mortality and improve quality of life compared to chronic dialysis. Given a limited supply of deceased donor kidneys, transplant professionals have increasingly focused attention on living kidney transplantation. Maximizing this vital resource for transplant candidates could substantially reduce the burdens of ESRD. Large and unexplained variation exists in the magnitude of living kidney transplantation across renal transplant centers. Comprehensive transplantation records from the United Network of Organ Sharing offer a valuable opportunity to elucidate the factors underlying this variation. Through the proposed project, Dr. Reese will measure magnitude of living kidney transplantation within and across transplant centers, and identify center attributes associated with variation in the magnitude of living kidney transplantation. Understanding how transplant centers optimize or limit their patients' opportunities to obtain a live donor kidney transplant represents a crucial advance in developing strategies to expand access to transplantation overall.

描述（由申请人提供）：

项目成果

期刊论文数量（22）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Donation after cardiac death liver transplantation is associated with increased risk of end-stage renal disease.

心脏死亡后的肝移植捐赠与终末期肾病的风险增加有关。

DOI：
10.1111/tri.12409
发表时间：
2014
期刊：
Transplant international : official journal of the European Society for Organ Transplantation
影响因子：
0
作者：
Ruebner,RebeccaL;Reese,PeterP;Abt,PeterL
通讯作者：
Abt,PeterL

Medical follow-up of living kidney donors by 1 year after nephrectomy.