EFFECTS OF INSTRUCTION ON METABOLIC RISK FACTORS ON LIFESTYLE CHOICES

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项研究的目的是确定医学院第一学期参与代谢风险因素的综合分析是否会影响医学院四年后的生活方式选择。 医学和公众对医生的期望已经发生了变化，而且是恰当的。等到疾病发生后再提供补救措施不再是可以接受的。预防是患者的权利。未来的医生不仅将根据他们诊断和治疗疾病的能力进行评判，而且还将根据他们预防导致疾病的异常的能力来进行评判。认识到危险因素会导致对高血压、血脂异常、肥胖、糖尿病、肺气肿等高危患者的特定治疗。人们越来越认识到，某些疾病是聚集性的。 许多情况都有共同的致病机制。当今最流行的概念之一是胰岛素抵抗综合征中的疾病集聚。聚集性表明，这些疾病共享一些共同的潜在风险因素。重点将放在胰岛素抵抗综合症中的风险因素上。综合临床研究中心邀请医学生参加医学院第一年的风险因素分析。已有600多名学生参与，项目热情极高。然而，该项目的设计并不是为了确定参与和随后的生活方式选择之间的联系。通过比较医学院第一年到第四年的结果和反应，可以评估该项目对参与者生活方式选择的影响。 医科学生将被邀请参加M-4学年最后四个月的研究。所有四年级的医学生都有资格参加，然而，那些参加了一年级医学研究的学生将被问及在这项研究中获得的数据是否可以与当前的数据联系起来进行分析。每名学生将被要求在GCRC住一晚。入学后不久，学生将接受GCRC营养师的采访。在采访期间，营养师将进行皮褶测量，以确定体脂百分比、BMI和腰围。学生将收集多次尿液用于氮分析，并采集血液用于测量血糖、胰岛素、空腹血脂和血液化学。届时将进行生物电阻抗检测。然后，学生们将被送往早餐，并从GCRC出院。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to determine if participation in a comprehensive analysis of metabolic risk factors during the first semester of medical school affects lifestyle choices after four years of medical school. Medicine and the expectations the public has of physicians has changed and appropriately so. No longer is it acceptable to wait until disease occurs and then offer remedies. Prevention is a patient right. Future physicians will be judges not only on their ability to diagnose and treat diseases but also by their ability to prevent the abnormalities responsible for the disease. Recognizing risk factors leads to specific therapy for high risk patients with hypertension, abnormal lipids, obesity, diabetes, emphysema, etc.. It is increasingly recognized that certain diseases cluster. Many conditions share a common pathogenetic mechanism. One of the most popular concepts today is that of disease clustering in the insulin resistance syndrome. Clustering suggests that the diseases share some common underlying risk factor. Emphasis will be places on risk factors within the insulin resistance syndrome. The General Clinical Research Center has invited medical students to participate in a risk factor analysis during the first year of medical school. More than 600 students have participated and the enthusiasm for the project has been excellent. However, the project was not designed to determine the association between participation and subsequent lifestyle choices. By comparing results and responses from the 1st to the 4th years of medical school, it is possible to assess the impact of the project on the lifestyle choices of those who participate. Medical students will be invited to participate in the study over the last four months of the M-4 year. All 4th year medical students will be eligible to participate, however, those students who participated in the 1st year medical study will be asked if data obtained during this study can be linked to the current data for analysis. Each student will be required to spend one night in the GCRC. Shortly after admission, the student will be interviewed by the GCRC nutritionist. During the interview, the nutritionist will perform skinfold measurements to determine percent bodyfat, BMI and waist circumference. The student will collect a times urine for nitrogen analysis and blood will be obtained for the measurement of glucose, insulin, fasting lipid profile, and blood chemistries. Bioelectrical impedance will be performed at that time. The students will then be given breakfast and discharged from the GCRC.