CLINICAL TRIAL: EFFICACY OF ANTIDEPRESSANTS IN CHRONIC BACK PAIN

临床试验：抗抑郁药治疗慢性背痛的疗效

• 批准号: 8166788
• 负责人: JOSEPH H ATKINSON
• 金额: $ 0.52万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-12-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8166788
• 关键词: Absence of pain sensation; Acute; Antidepressive Agents; Clinical Trials; Computer Retrieval of Information on Scientific Projects Database; Desipramine; Fluoxetine; Funding; Grant; Institution; Pain; Patients; Placebos; Research; Research Personnel; Resources; Safety; Source; United States National Institutes of Health; chronic back pain; depressive symptoms; disability; prospective; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Examine the acute efficacy and safety of desipramine alone compared to fluoxetine alone and to placebo in treating pain, disability and depressive symptoms in patients with chronic back pain. Develop prospective concentration-response curves for desipramine and fluoxetine analgesia.

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 比较地昔帕明单药与氟西汀单药和安慰剂治疗慢性背痛患者疼痛、残疾和抑郁症状的急性疗效和安全性。绘制地昔帕明和氟西汀镇痛的前瞻性浓度-反应曲线。