IDENTIFYING PRESUMPTIVE CELIAC DISEASE IN HIGH RISK POPULATIONS

识别高危人群中的疑似乳糜泻

• 批准号: 8166883
• 负责人: Martin Frederick KAGNOFF
• 金额: $ 1.05万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-12-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8166883
• 关键词: Antibodies; Celiac Disease; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Immunoglobulin A; Institution; Patients; Population; Prevalence; Research; Research Personnel; Resources; Risk; Risk Factors; Screening procedure; Serum; Source; Symptoms; Tissues; Transglutaminases; United States National Institutes of Health; base; high risk

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. 1) Determine the prevalence of positive serum IgA tissue transglutaminase antibody among populations at increased risk for celiac disease and who have limited access to antibody-based screening. 2) Determine the prevalence of risk factors, symptoms, and duration of symptoms among populations at high risk for celiac disease and limited access to antibody-based screening 3) Determine the major reasons why patients seek antibody-based screening for celiac disease. 4) Determine the barriers to obtaining antibody-based screening for celiac disease.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 1)确定血清IgA组织转谷氨酰胺酶抗体阳性在乳糜泻高危人群和获得基于抗体的筛查机会有限的人群中的流行率。 2)确定乳糜泻高危人群和有限的抗体筛查人群中的风险因素、症状和症状持续时间 3)确定患者寻求以抗体为基础的乳糜泻筛查的主要原因。 4)确定获得基于抗体的乳糜泻筛查的障碍。