GENETICS OF EARLY LUPUS AUTOIMMUNITY IN AFRICAN AMERICANS

非裔美国人早期狼疮自身免疫的遗传学

• 批准号: 8168262
• 负责人: Courtney Montgomery
• 金额: $ 16.29万
• 依托单位: OKLAHOMA MEDICAL RESEARCH FOUNDATION
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-01 至 2011-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8168262
• 关键词: African American; Antibodies; Autoantibodies; Autoimmunity; Clinical; Computer Retrieval of Information on Scientific Projects Database; Development; Disease; Funding; Genetic; Genetic Determinism; Genotype; Grant; Institution; Lupus; Phase; Research; Research Personnel; Resources; Sampling; Source; United States National Institutes of Health

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The primary objective of this project will be to identify the genetic determinants of autoantibody formation what occurs before the development of clinical disease. The first phase will be to determine the autoantibody profile in samples that have already been genotyped. The second phase will be to replicate these findings in a second set of samples typed for both antibody profile and genotype at specific loci.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 该项目的主要目的是确定自身抗体形成的遗传决定因素，在临床疾病发展之前发生的事情。第一阶段将是确定已经被基因型的样品中的自身抗体曲线。第二阶段将是在特定基因座的第二组样品中复制这些发现。