IDENTIFICATION/CHARACTERIZATION OF VIRUS-INDUCED CELL DEATH GENES IN NICOTIANA

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 植物病毒在寄主上引起的特有症状是病毒与寄主基因产物相互作用的结果。虽然已被证明相对容易地识别负责症状发展或寄主范围确定的植物病毒基因，但这些基因产物引起特定反应或影响寄主范围的机制仍未完全了解。本研究试图确定烟草花叶病毒引起的烟草过敏反应和烟草摇铃病毒诱导的烟草精品烟草系统细胞死亡的病毒和植物基因。从这些寄主-病原体系统获得的信息将为更好地理解这些病毒如何引起不同的细胞死亡反应提供更多的信息，并为植物病毒诱导症状的机制提供新的见解。此外，这个项目使本科生接触到分子生物学、分子植物病理学以及生物技术在植物保护中的有益应用。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The characteristic symptoms induced by a plant virus on its host result from the interactions between viral and host gene products. While it has been proven to be relatively easy to identify plant virus genes responsible for symptom development or for host range determination, the mechanisms by which these gene products elicit specific responses or influence host range remain to be fully understood. My research attempts to characterize the viral and plant genes responsible for the hypersensitive response elicited in Nicotiana gossei by Tobacco mosaic virus and the systemic cell death induced in Nicotiana excelsior by Tobacco rattle virus. The information gained from these host-pathogen systems will provide a greater understanding of how these viruses elicit different cell death responses and new insights into the mechanisms of plant virus-induced symptoms. Furthermore, this project exposes undergraduate students to the areas of molecular biology, molecular plant pathology, and the beneficial uses of biotechnology in plant protection.